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A “Lymphocyte MicroRNA Signature” as Predictive Biomarker of Immunotherapy Response and Plasma PD-1/PD-L1 Expression Levels in Patients with Metastatic Renal Cell Carcinoma: Pointing towards Epigenetic Reprogramming

SIMPLE SUMMARY: MicroRNAs are small molecules of non-coding RNAs which regulate gene expression at the post-transcriptional level. Normal miRNA expression and function can be deregulated in cancer. The comprehensive molecular characterization of Renal Cell Carcinoma shows several genes silenced and...

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Detalles Bibliográficos
Autores principales: Incorvaia, Lorena, Fanale, Daniele, Badalamenti, Giuseppe, Brando, Chiara, Bono, Marco, De Luca, Ida, Algeri, Laura, Bonasera, Annalisa, Corsini, Lidia Rita, Scurria, Salvatore, Iovanna, Juan Lucio, Russo, Antonio, Bazan, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697734/
https://www.ncbi.nlm.nih.gov/pubmed/33207823
http://dx.doi.org/10.3390/cancers12113396

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