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Handwriting Analysis in Children and Adolescents with Hemophilia: A Pilot Study

Background: Handwriting is a complex task that requires the integrity of different sensorimotor components to be performed successfully. Patients with hemophilia suffer from recurrent joint bleeds that may occur in the elbow, causing elbow dysfunction with handwriting performance impairment. In our...

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Autores principales: Pasta, Gianluigi, Mancuso, Maria Elisa, De Felice, Filomena, Seuser, Alexander, Annunziata, Salvatore, Peyvandi, Flora, Santagostino, Elena, Mosconi, Mario, Seuser, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697872/
https://www.ncbi.nlm.nih.gov/pubmed/33202574
http://dx.doi.org/10.3390/jcm9113663
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author Pasta, Gianluigi
Mancuso, Maria Elisa
De Felice, Filomena
Seuser, Alexander
Annunziata, Salvatore
Peyvandi, Flora
Santagostino, Elena
Mosconi, Mario
Seuser, Axel
author_facet Pasta, Gianluigi
Mancuso, Maria Elisa
De Felice, Filomena
Seuser, Alexander
Annunziata, Salvatore
Peyvandi, Flora
Santagostino, Elena
Mosconi, Mario
Seuser, Axel
author_sort Pasta, Gianluigi
collection PubMed
description Background: Handwriting is a complex task that requires the integrity of different sensorimotor components to be performed successfully. Patients with hemophilia suffer from recurrent joint bleeds that may occur in the elbow, causing elbow dysfunction with handwriting performance impairment. In our study, we described instrumental dysgraphia that is related to functional disturbances. This pilot study aims to evaluate the handwriting performance in a group of patients with hemophilia. Methods: The study was performed at the Angelo Bianchi Bonomi Hemophilia and Thrombosis Center in Milan. Boys with severe and moderate hemophilia A and B regularly followed-up at that Center, with age between 6–19 years, were eligible. Patients were invited to the Center for one multidisciplinary evaluation of the upper limbs that included: Clinical examination, surface electromyography, and handwriting assessment. Results: All patients, but one, completed handwriting assessment. Overall, 14/19 (74%) had abnormal handwriting, which was overt instrumental dysgraphia in six (32%). There was no difference in Hemophilia Joint Health Score (HJHS) between dysgraphic and non-dysgraphic boys, while surface electromyography (sEMG) revealed a prevalence of flexor muscles of the upper limb in dysgraphic as compared with non-dysgraphic boys. Conclusions: The rather high prevalence of instrumental dysgraphia found in this pilot study deserves a further development of this preliminary experience by increasing the number of examined patients and comparing them with a control group, including quality of life and psychological assessment.
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spelling pubmed-76978722020-11-29 Handwriting Analysis in Children and Adolescents with Hemophilia: A Pilot Study Pasta, Gianluigi Mancuso, Maria Elisa De Felice, Filomena Seuser, Alexander Annunziata, Salvatore Peyvandi, Flora Santagostino, Elena Mosconi, Mario Seuser, Axel J Clin Med Article Background: Handwriting is a complex task that requires the integrity of different sensorimotor components to be performed successfully. Patients with hemophilia suffer from recurrent joint bleeds that may occur in the elbow, causing elbow dysfunction with handwriting performance impairment. In our study, we described instrumental dysgraphia that is related to functional disturbances. This pilot study aims to evaluate the handwriting performance in a group of patients with hemophilia. Methods: The study was performed at the Angelo Bianchi Bonomi Hemophilia and Thrombosis Center in Milan. Boys with severe and moderate hemophilia A and B regularly followed-up at that Center, with age between 6–19 years, were eligible. Patients were invited to the Center for one multidisciplinary evaluation of the upper limbs that included: Clinical examination, surface electromyography, and handwriting assessment. Results: All patients, but one, completed handwriting assessment. Overall, 14/19 (74%) had abnormal handwriting, which was overt instrumental dysgraphia in six (32%). There was no difference in Hemophilia Joint Health Score (HJHS) between dysgraphic and non-dysgraphic boys, while surface electromyography (sEMG) revealed a prevalence of flexor muscles of the upper limb in dysgraphic as compared with non-dysgraphic boys. Conclusions: The rather high prevalence of instrumental dysgraphia found in this pilot study deserves a further development of this preliminary experience by increasing the number of examined patients and comparing them with a control group, including quality of life and psychological assessment. MDPI 2020-11-14 /pmc/articles/PMC7697872/ /pubmed/33202574 http://dx.doi.org/10.3390/jcm9113663 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pasta, Gianluigi
Mancuso, Maria Elisa
De Felice, Filomena
Seuser, Alexander
Annunziata, Salvatore
Peyvandi, Flora
Santagostino, Elena
Mosconi, Mario
Seuser, Axel
Handwriting Analysis in Children and Adolescents with Hemophilia: A Pilot Study
title Handwriting Analysis in Children and Adolescents with Hemophilia: A Pilot Study
title_full Handwriting Analysis in Children and Adolescents with Hemophilia: A Pilot Study
title_fullStr Handwriting Analysis in Children and Adolescents with Hemophilia: A Pilot Study
title_full_unstemmed Handwriting Analysis in Children and Adolescents with Hemophilia: A Pilot Study
title_short Handwriting Analysis in Children and Adolescents with Hemophilia: A Pilot Study
title_sort handwriting analysis in children and adolescents with hemophilia: a pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697872/
https://www.ncbi.nlm.nih.gov/pubmed/33202574
http://dx.doi.org/10.3390/jcm9113663
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