Development and Validation of Stability-Indicating HPLC Methods for the Estimation of Lomefloxacin and Balofloxacin Oxidation Process under ACVA, H(2)O(2), or KMnO(4) Treatment. Kinetic Evaluation and Identification of Degradation Products by Mass Spectrometry

The oxidation of lomefloxacin (LOM) and balofloxacin (BAL) under the influence of azo initiator of radical reactions of 4,4′-azobis(4-cyanopentanoic acid) (ACVA) and H(2)O(2) was examined. Oxidation using H(2)O(2) was performed at room temperature while using ACVA at temperatures: 40, 50, 60 °C. Add...

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Detalles Bibliográficos
Autores principales: Żuromska-Witek, Barbara, Żmudzki, Paweł, Szlósarczyk, Marek, Maślanka, Anna, Hubicka, Urszula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697971/
https://www.ncbi.nlm.nih.gov/pubmed/33187198
http://dx.doi.org/10.3390/molecules25225251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697971/
https://www.ncbi.nlm.nih.gov/pubmed/33187198
http://dx.doi.org/10.3390/molecules25225251

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