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Development and Validation of Stability-Indicating HPLC Methods for the Estimation of Lomefloxacin and Balofloxacin Oxidation Process under ACVA, H(2)O(2), or KMnO(4) Treatment. Kinetic Evaluation and Identification of Degradation Products by Mass Spectrometry
The oxidation of lomefloxacin (LOM) and balofloxacin (BAL) under the influence of azo initiator of radical reactions of 4,4′-azobis(4-cyanopentanoic acid) (ACVA) and H(2)O(2) was examined. Oxidation using H(2)O(2) was performed at room temperature while using ACVA at temperatures: 40, 50, 60 °C. Add...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697971/ https://www.ncbi.nlm.nih.gov/pubmed/33187198 http://dx.doi.org/10.3390/molecules25225251 |