Spontaneous Remission and Concomitant Progression in a Patient with DLBCL

Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma. Although DLBCL can be cured in more than half of all patients, up to 50% of patients become refractory to initial treatment or relapse after complete remission. We present a case of complete spontaneous remission of some tumo...

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Detalles Bibliográficos
Autores principales: Han, Eun Ji, Kim, Jihyun, Park, Suk Young, O, Joo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7697978/
https://www.ncbi.nlm.nih.gov/pubmed/33202678
http://dx.doi.org/10.3390/diagnostics10110950
Descripción
Sumario:Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma. Although DLBCL can be cured in more than half of all patients, up to 50% of patients become refractory to initial treatment or relapse after complete remission. We present a case of complete spontaneous remission of some tumors and concomitant newly developed tumors observed in a patient with relapsed DLBCL. Spontaneous remission of lymphoma without treatment is a rare phenomenon and can occur at baseline as well as in relapsed DLBCL. However, most patients who initially experience spontaneous remission later develop relapse. Thus, careful follow-up is required, and fluorine-18-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET)/computed tomography (CT) allows monitoring of multiple lesions.

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