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ROS-Induced SIRT2 Upregulation Contributes to Cisplatin Sensitivity in Ovarian Cancer

Cisplatin resistance remains a significant obstacle for improving the clinical outcome of ovarian cancer patients. Recent studies have demonstrated that cisplatin is an important inducer of intracellullar reactive oxygen species (ROS), triggering cancer cell death. Sirtuin 2 (SIRT2), a member of cla...

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Detalles Bibliográficos
Autores principales:	Wang, Wenyu, Im, Jihye, Kim, Soochi, Jang, Suin, Han, Youngjin, Yang, Kyung-Min, Kim, Seong-Jin, Dhanasekaran, Danny N., Song, Yong Sang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698236/ https://www.ncbi.nlm.nih.gov/pubmed/33207824 http://dx.doi.org/10.3390/antiox9111137

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