Stability of Engineered Micro or Nanobubbles for Biomedical Applications

A micro/nanobubble (MNB) refers to a bubble structure sized in a micrometer or nanometer scale, in which the core is separated from the external environment and is normally made of gas. Recently, it has been confirmed that MNBs can be widely used in angiography, drug delivery, and treatment. Thus, M...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Beomjin, Yoon, Semi, Choi, Yonghyun, Jang, Jaehee, Park, Soomin, Choi, Jonghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698255/
https://www.ncbi.nlm.nih.gov/pubmed/33202709
http://dx.doi.org/10.3390/pharmaceutics12111089
_version_ 1783615788218843136
author Park, Beomjin
Yoon, Semi
Choi, Yonghyun
Jang, Jaehee
Park, Soomin
Choi, Jonghoon
author_facet Park, Beomjin
Yoon, Semi
Choi, Yonghyun
Jang, Jaehee
Park, Soomin
Choi, Jonghoon
author_sort Park, Beomjin
collection PubMed
description A micro/nanobubble (MNB) refers to a bubble structure sized in a micrometer or nanometer scale, in which the core is separated from the external environment and is normally made of gas. Recently, it has been confirmed that MNBs can be widely used in angiography, drug delivery, and treatment. Thus, MNBs are attracting attention as they are capable of constructing a new contrast agent or drug delivery system. Additionally, in order to effectively use an MNB, the method of securing its stability is also being studied. This review highlights the factors affecting the stability of an MNB and the stability of the MNB within the ultrasonic field. It also discusses the relationship between the stability of the bubble and its applicability in vivo.
format Online
Article
Text
id pubmed-7698255
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-76982552020-11-29 Stability of Engineered Micro or Nanobubbles for Biomedical Applications Park, Beomjin Yoon, Semi Choi, Yonghyun Jang, Jaehee Park, Soomin Choi, Jonghoon Pharmaceutics Review A micro/nanobubble (MNB) refers to a bubble structure sized in a micrometer or nanometer scale, in which the core is separated from the external environment and is normally made of gas. Recently, it has been confirmed that MNBs can be widely used in angiography, drug delivery, and treatment. Thus, MNBs are attracting attention as they are capable of constructing a new contrast agent or drug delivery system. Additionally, in order to effectively use an MNB, the method of securing its stability is also being studied. This review highlights the factors affecting the stability of an MNB and the stability of the MNB within the ultrasonic field. It also discusses the relationship between the stability of the bubble and its applicability in vivo. MDPI 2020-11-13 /pmc/articles/PMC7698255/ /pubmed/33202709 http://dx.doi.org/10.3390/pharmaceutics12111089 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Park, Beomjin
Yoon, Semi
Choi, Yonghyun
Jang, Jaehee
Park, Soomin
Choi, Jonghoon
Stability of Engineered Micro or Nanobubbles for Biomedical Applications
title Stability of Engineered Micro or Nanobubbles for Biomedical Applications
title_full Stability of Engineered Micro or Nanobubbles for Biomedical Applications
title_fullStr Stability of Engineered Micro or Nanobubbles for Biomedical Applications
title_full_unstemmed Stability of Engineered Micro or Nanobubbles for Biomedical Applications
title_short Stability of Engineered Micro or Nanobubbles for Biomedical Applications
title_sort stability of engineered micro or nanobubbles for biomedical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698255/
https://www.ncbi.nlm.nih.gov/pubmed/33202709
http://dx.doi.org/10.3390/pharmaceutics12111089
work_keys_str_mv AT parkbeomjin stabilityofengineeredmicroornanobubblesforbiomedicalapplications
AT yoonsemi stabilityofengineeredmicroornanobubblesforbiomedicalapplications
AT choiyonghyun stabilityofengineeredmicroornanobubblesforbiomedicalapplications
AT jangjaehee stabilityofengineeredmicroornanobubblesforbiomedicalapplications
AT parksoomin stabilityofengineeredmicroornanobubblesforbiomedicalapplications
AT choijonghoon stabilityofengineeredmicroornanobubblesforbiomedicalapplications

Ejemplares similares