The Molecular and Functional Characteristics of HLA-G and the Interaction with Its Receptors: Where to Intervene for Cancer Immunotherapy?

Human leukocyte antigen G (HLA-G) mediates maternal-fetal immune tolerance. It is also considered an immune checkpoint in cancer since it may mediate immune evasion and thus promote tumor growth. HLA-G is, therefore, a potential target for immunotherapy. However, existing monoclonal antibodies direc...

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Detalles Bibliográficos
Autores principales: Attia, Jiji V. D., Dessens, Charlotte E., van de Water, Ricky, Houvast, Ruben D., Kuppen, Peter J. K., Krijgsman, Daniëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698525/
https://www.ncbi.nlm.nih.gov/pubmed/33213057
http://dx.doi.org/10.3390/ijms21228678

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