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Racial disparities in COVID-19 hospitalizations do not lead to disparities in outcomes

OBJECTIVES: The objective of the study is the identification of racial differences in characteristics and comorbidities in patients hospitalized for COVID-19 and the impact on outcomes. STUDY DESIGN: The study design is a retrospective observational study. METHODS: Data for all patients admitted to...

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Autores principales: Krishnamoorthy, G., Arsene, C., Jena, N., Mogulla, S.M., Coakley, R., Khine, J., Khosrodad, N., Klein, A., Sule, A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society for Public Health. Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698674/
https://www.ncbi.nlm.nih.gov/pubmed/33385640
http://dx.doi.org/10.1016/j.puhe.2020.11.021
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author Krishnamoorthy, G.
Arsene, C.
Jena, N.
Mogulla, S.M.
Coakley, R.
Khine, J.
Khosrodad, N.
Klein, A.
Sule, A.A.
author_facet Krishnamoorthy, G.
Arsene, C.
Jena, N.
Mogulla, S.M.
Coakley, R.
Khine, J.
Khosrodad, N.
Klein, A.
Sule, A.A.
author_sort Krishnamoorthy, G.
collection PubMed
description OBJECTIVES: The objective of the study is the identification of racial differences in characteristics and comorbidities in patients hospitalized for COVID-19 and the impact on outcomes. STUDY DESIGN: The study design is a retrospective observational study. METHODS: Data for all patients admitted to seven community hospitals in Michigan, United States, with polymerase chain reaction confirmed diagnosis of COVID-19 from March 10 to April 15, 2020 were analyzed. The primary outcomes of racial disparity in inpatient mortality and intubation were analyzed using descriptive statistics and multivariate regression models. RESULTS: The study included 336 Black and 408 White patients. Black patients were younger (62.9 ± 15.0 years vs 71.8 ± 16.4, P < .001), had a higher mean body mass index (32.4 ± 8.6 kg/m(2) vs 28.8 ± 7.5, P < .001), had higher prevalence of diabetes (136/336 vs 130/408, P = .02), and presented later (6.6 ± 5.3 days after symptom onset vs. 5.4 ± 5.4, P = .006) compared with White patients. Younger Black patients had a higher prevalence of obesity (age <65 years, 69.9%) than older Black patients (age >65 years, 39.2%) and younger White patients (age < 65, 55.1%). Intubation did not reach statistical significance for racial difference (Black patients 61/335 vs. 54/406, P = .08). Mortality was not higher in Black patients (65/335 vs. 142/406 in White patients, odds ratio 0.61, 95% confidence interval: 0.37 to 0.99, 2-sided P = .05) in multivariate analysis, accounting for other risk factors associated with mortality. CONCLUSIONS: Higher prevalence of obesity and diabetes in young Black populations may be the critical factor driving disproportionate COVID-19 hospitalizations in Black populations. Hospitalized Black patients do not have worse outcomes compared with White patients.
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spelling pubmed-76986742020-12-01 Racial disparities in COVID-19 hospitalizations do not lead to disparities in outcomes Krishnamoorthy, G. Arsene, C. Jena, N. Mogulla, S.M. Coakley, R. Khine, J. Khosrodad, N. Klein, A. Sule, A.A. Public Health Original Research OBJECTIVES: The objective of the study is the identification of racial differences in characteristics and comorbidities in patients hospitalized for COVID-19 and the impact on outcomes. STUDY DESIGN: The study design is a retrospective observational study. METHODS: Data for all patients admitted to seven community hospitals in Michigan, United States, with polymerase chain reaction confirmed diagnosis of COVID-19 from March 10 to April 15, 2020 were analyzed. The primary outcomes of racial disparity in inpatient mortality and intubation were analyzed using descriptive statistics and multivariate regression models. RESULTS: The study included 336 Black and 408 White patients. Black patients were younger (62.9 ± 15.0 years vs 71.8 ± 16.4, P < .001), had a higher mean body mass index (32.4 ± 8.6 kg/m(2) vs 28.8 ± 7.5, P < .001), had higher prevalence of diabetes (136/336 vs 130/408, P = .02), and presented later (6.6 ± 5.3 days after symptom onset vs. 5.4 ± 5.4, P = .006) compared with White patients. Younger Black patients had a higher prevalence of obesity (age <65 years, 69.9%) than older Black patients (age >65 years, 39.2%) and younger White patients (age < 65, 55.1%). Intubation did not reach statistical significance for racial difference (Black patients 61/335 vs. 54/406, P = .08). Mortality was not higher in Black patients (65/335 vs. 142/406 in White patients, odds ratio 0.61, 95% confidence interval: 0.37 to 0.99, 2-sided P = .05) in multivariate analysis, accounting for other risk factors associated with mortality. CONCLUSIONS: Higher prevalence of obesity and diabetes in young Black populations may be the critical factor driving disproportionate COVID-19 hospitalizations in Black populations. Hospitalized Black patients do not have worse outcomes compared with White patients. The Royal Society for Public Health. Published by Elsevier Ltd. 2021-01 2020-11-28 /pmc/articles/PMC7698674/ /pubmed/33385640 http://dx.doi.org/10.1016/j.puhe.2020.11.021 Text en © 2020 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Research
Krishnamoorthy, G.
Arsene, C.
Jena, N.
Mogulla, S.M.
Coakley, R.
Khine, J.
Khosrodad, N.
Klein, A.
Sule, A.A.
Racial disparities in COVID-19 hospitalizations do not lead to disparities in outcomes
title Racial disparities in COVID-19 hospitalizations do not lead to disparities in outcomes
title_full Racial disparities in COVID-19 hospitalizations do not lead to disparities in outcomes
title_fullStr Racial disparities in COVID-19 hospitalizations do not lead to disparities in outcomes
title_full_unstemmed Racial disparities in COVID-19 hospitalizations do not lead to disparities in outcomes
title_short Racial disparities in COVID-19 hospitalizations do not lead to disparities in outcomes
title_sort racial disparities in covid-19 hospitalizations do not lead to disparities in outcomes
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698674/
https://www.ncbi.nlm.nih.gov/pubmed/33385640
http://dx.doi.org/10.1016/j.puhe.2020.11.021
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