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Formulation of Liver-Specific PLGA-DY-635 Nanoparticles Loaded with the Protein Kinase C Inhibitor Bisindolylmaleimide I

Bisindolylmaleimide I (BIM-I) is a competitive pan protein kinase C inhibitor with anti-inflammatory and anti-metastatic properties, suggested to treat inflammatory diseases and various cancer entities. However, despite its therapeutic potential, BIM-I has two major drawbacks, i.e., it has a poor wa...

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Detalles Bibliográficos
Autores principales: Shkodra, Blerina, Press, Adrian T., Vollrath, Antje, Nischang, Ivo, Schubert, Stephanie, Hoeppener, Stephanie, Haas, Dorothee, Enzensperger, Christoph, Lehmann, Marc, Babic, Petra, Benecke, Kay Jovana, Traeger, Anja, Bauer, Michael, Schubert, Ulrich S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698893/
https://www.ncbi.nlm.nih.gov/pubmed/33218172
http://dx.doi.org/10.3390/pharmaceutics12111110