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The Δ133p53 Isoforms, Tuners of the p53 Pathway
SIMPLE SUMMARY: TP53, the most frequently mutated gene in human cancers, has a key role in the maintenance of the genetic stability and, thus, in preventing tumor development. The p53-dependent responses were long thought to be solely driven by canonical p53α. However, it is now known that TP53 phys...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698932/ https://www.ncbi.nlm.nih.gov/pubmed/33218139 http://dx.doi.org/10.3390/cancers12113422 |