SPDR-01 Paired epithelioid glioblastoma patient-derived xenograft models to evaluate resistant mechanism for molecular target therapy

Epithelioid glioblastoma (E-GBM) arises at younger age, commonly disseminates to cerebrospinal fluid, and results in dismal prognosis. About half of E-GBM harbors BRAF V600E mutation, thus BRAF/MEK inhibitors are expected to be specifically sensitive to E-GBM like other BRAF V600E mutant carcinomas....

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Detalles Bibliográficos
Autores principales: Sasame, Jo, Tateishi, Kensuke, Ikegaya, Naoki, Miyake, Yohei, Nakamura, Taishi, Udaka, Naoko, Yamanaka, Shoji, Yamamoto, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699076/
http://dx.doi.org/10.1093/noajnl/vdaa143.020

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