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ET-05 Alectinib and ceritinib, the second-generation ALK inhibitors, effectively induce glioblastoma cell death

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that only expresses in the developmental stage of the central and peripheral nervous system. A variety of ALK gene alterations, such as oncogenic fusion, activating point mutation, or wild type gene amplification, have been recently disc...

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Detalles Bibliográficos
Autores principales: Kawauchi, Daisuke, Takahashi, Masamichi, Yamamuro, Shun, Kobayashi, Tatsuya, Uchida, Eita, Iwadate, Yasuo, Ichimura, Koichi, Tomiyama, Arata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699108/
http://dx.doi.org/10.1093/noajnl/vdaa143.025