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Chemical Compounds and Biologic Activities: A Review of Cedrela Genus

The genus Cedrela P. Browne, which belongs to the Meliaceae family, has eighteen species. Trees of this genus are of economic interest due to wood quality, as well as being the focus of studies because of relevant biologic activities as in other Meliaceae species. These activities are mainly related...

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Autores principales: Nogueira, Thalya Soares R., Passos, Michel de S., Nascimento, Lara Pessanha S., Arantes, Mayara Barreto de S., Monteiro, Noemi O., Boeno, Samyra Imad da S., de Carvalho Junior, Almir, Azevedo, Otoniel de A., Terra, Wagner da S., Vieira, Milena Gonçalves C., Braz-Filho, Raimundo, Curcino Vieira, Ivo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699174/
https://www.ncbi.nlm.nih.gov/pubmed/33218181
http://dx.doi.org/10.3390/molecules25225401
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author Nogueira, Thalya Soares R.
Passos, Michel de S.
Nascimento, Lara Pessanha S.
Arantes, Mayara Barreto de S.
Monteiro, Noemi O.
Boeno, Samyra Imad da S.
de Carvalho Junior, Almir
Azevedo, Otoniel de A.
Terra, Wagner da S.
Vieira, Milena Gonçalves C.
Braz-Filho, Raimundo
Curcino Vieira, Ivo J.
author_facet Nogueira, Thalya Soares R.
Passos, Michel de S.
Nascimento, Lara Pessanha S.
Arantes, Mayara Barreto de S.
Monteiro, Noemi O.
Boeno, Samyra Imad da S.
de Carvalho Junior, Almir
Azevedo, Otoniel de A.
Terra, Wagner da S.
Vieira, Milena Gonçalves C.
Braz-Filho, Raimundo
Curcino Vieira, Ivo J.
author_sort Nogueira, Thalya Soares R.
collection PubMed
description The genus Cedrela P. Browne, which belongs to the Meliaceae family, has eighteen species. Trees of this genus are of economic interest due to wood quality, as well as being the focus of studies because of relevant biologic activities as in other Meliaceae species. These activities are mainly related to limonoids, a characteristic class of compounds in this family. Therefore, the aim of this review is to perform a survey of the citations in the literature on the Cedrela genus species. Articles were found on quantitative and qualitative phytochemical studies of the Cedrela species, revealing the chemical compounds identified, such as aliphatics acid and alcohol, flavonoids, tocopherol, monoterpenes, sesquiterpenes, triterpenes, cycloartanes, steroids, and limonoids. Although some activities were tested, the majority of studies focused on the insecticidal, antifeedant, or insect growth inhibitor activities of this genus. Nonetheless, the most promising activities were related to their antimalarial and antitripanocidal effects, although further investigations are still needed.
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spelling pubmed-76991742020-11-29 Chemical Compounds and Biologic Activities: A Review of Cedrela Genus Nogueira, Thalya Soares R. Passos, Michel de S. Nascimento, Lara Pessanha S. Arantes, Mayara Barreto de S. Monteiro, Noemi O. Boeno, Samyra Imad da S. de Carvalho Junior, Almir Azevedo, Otoniel de A. Terra, Wagner da S. Vieira, Milena Gonçalves C. Braz-Filho, Raimundo Curcino Vieira, Ivo J. Molecules Review The genus Cedrela P. Browne, which belongs to the Meliaceae family, has eighteen species. Trees of this genus are of economic interest due to wood quality, as well as being the focus of studies because of relevant biologic activities as in other Meliaceae species. These activities are mainly related to limonoids, a characteristic class of compounds in this family. Therefore, the aim of this review is to perform a survey of the citations in the literature on the Cedrela genus species. Articles were found on quantitative and qualitative phytochemical studies of the Cedrela species, revealing the chemical compounds identified, such as aliphatics acid and alcohol, flavonoids, tocopherol, monoterpenes, sesquiterpenes, triterpenes, cycloartanes, steroids, and limonoids. Although some activities were tested, the majority of studies focused on the insecticidal, antifeedant, or insect growth inhibitor activities of this genus. Nonetheless, the most promising activities were related to their antimalarial and antitripanocidal effects, although further investigations are still needed. MDPI 2020-11-18 /pmc/articles/PMC7699174/ /pubmed/33218181 http://dx.doi.org/10.3390/molecules25225401 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Nogueira, Thalya Soares R.
Passos, Michel de S.
Nascimento, Lara Pessanha S.
Arantes, Mayara Barreto de S.
Monteiro, Noemi O.
Boeno, Samyra Imad da S.
de Carvalho Junior, Almir
Azevedo, Otoniel de A.
Terra, Wagner da S.
Vieira, Milena Gonçalves C.
Braz-Filho, Raimundo
Curcino Vieira, Ivo J.
Chemical Compounds and Biologic Activities: A Review of Cedrela Genus
title Chemical Compounds and Biologic Activities: A Review of Cedrela Genus
title_full Chemical Compounds and Biologic Activities: A Review of Cedrela Genus
title_fullStr Chemical Compounds and Biologic Activities: A Review of Cedrela Genus
title_full_unstemmed Chemical Compounds and Biologic Activities: A Review of Cedrela Genus
title_short Chemical Compounds and Biologic Activities: A Review of Cedrela Genus
title_sort chemical compounds and biologic activities: a review of cedrela genus
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699174/
https://www.ncbi.nlm.nih.gov/pubmed/33218181
http://dx.doi.org/10.3390/molecules25225401
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