High-Glucose-Induced Rab20 Upregulation Disrupts Gap Junction Intercellular Communication and Promotes Apoptosis in Retinal Endothelial and Müller Cells: Implications for Diabetic Retinopathy

To investigate whether high glucose (HG) alters Rab20 expression and compromises gap junction intercellular communication (GJIC) and cell survival, retinal cells were studied for altered intracellular trafficking of connexin 43 (Cx43). Retinal endothelial cells (RRECs) and retinal Müller cells (rMCs...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Dongjoon, Lewis, Casey Stottrup, Sarthy, Vijay P., Roy, Sayon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699280/
https://www.ncbi.nlm.nih.gov/pubmed/33227912
http://dx.doi.org/10.3390/jcm9113710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699280/
https://www.ncbi.nlm.nih.gov/pubmed/33227912
http://dx.doi.org/10.3390/jcm9113710

Ejemplares similares