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Sonic Hedgehog Signature in Pediatric Primary Bone Tumors: Effects of the GLI Antagonist GANT61 on Ewing’s Sarcoma Tumor Growth

SIMPLE SUMMARY: The poor clinical outcomes for Osteosarcoma (OS) and Ewing’s sarcoma (ES) patients underscore the urgency of developing novel therapeutic strategies for these pathologies. In this context, the emerging role of Sonic hedgehog (SHH) signaling in cancer has been critically evaluated, fo...

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Detalles Bibliográficos
Autores principales:	Mullard, Mathilde, Cadé, Marie, Morice, Sarah, Dupuy, Maryne, Danieau, Geoffroy, Amiaud, Jérome, Renault, Sarah, Lézot, Frédéric, Brion, Régis, Thepault, Rose Anne, Ory, Benjamin, Lamoureux, François, Corre, Isabelle, Brounais-LeRoyer, Bénédicte, Rédini, Françoise, Verrecchia, Franck
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699338/ https://www.ncbi.nlm.nih.gov/pubmed/33228057 http://dx.doi.org/10.3390/cancers12113438

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