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Effects of Continuous Intake of Rosemary Extracts on Mental Health in Working Generation Healthy Japanese Men: Post-Hoc Testing of a Randomized Controlled Trial

We previously performed a 4 week interventional trial that suggested that continuous intake of rosemary extract improves the mood states, fatigue, and cognitive function of working generation healthy adult Japanese men. However, the severity of depression in participants in our previous study was re...

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Autores principales: Araki, Risa, Sasaki, Kazunori, Onda, Hiroyuki, Nakamura, Syunsuke, Kassai, Masahiro, Kaneko, Toshiyuki, Isoda, Hiroko, Hashimoto, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699484/
https://www.ncbi.nlm.nih.gov/pubmed/33233510
http://dx.doi.org/10.3390/nu12113551
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author Araki, Risa
Sasaki, Kazunori
Onda, Hiroyuki
Nakamura, Syunsuke
Kassai, Masahiro
Kaneko, Toshiyuki
Isoda, Hiroko
Hashimoto, Koichi
author_facet Araki, Risa
Sasaki, Kazunori
Onda, Hiroyuki
Nakamura, Syunsuke
Kassai, Masahiro
Kaneko, Toshiyuki
Isoda, Hiroko
Hashimoto, Koichi
author_sort Araki, Risa
collection PubMed
description We previously performed a 4 week interventional trial that suggested that continuous intake of rosemary extract improves the mood states, fatigue, and cognitive function of working generation healthy adult Japanese men. However, the severity of depression in participants in our previous study was relatively mild. Therefore, in the present study, a post-hoc analysis of our previous study was conducted, limited to participants whose total mood disturbance (TMD) scores, which indicate greater mood disturbance, were above the median at baseline, to evaluate whether rosemary extract was effective for individuals with poor mental health. Following the intervention, the scores of TMD and “Confusion-Bewilderment” were significantly decreased (both p < 0.05), and scores of “Vigor-Activity” were significantly increased in the rosemary group (n = 8) compared with those in the control group (n = 13; p < 0.01). When comparing the scores from pre- and post-intervention, significant improvements in “Tension-Anxiety”, “Vigor-Activity”, “Fatigue on awakening”, “Daytime sleepiness”, and “Psychomotor speed” were observed in the rosemary group only (all p < 0.05). Based on these results, it was expected that rosemary extracts were effective for improving the mental energy and sleep quality of work-age men with poor mental health.
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spelling pubmed-76994842020-11-29 Effects of Continuous Intake of Rosemary Extracts on Mental Health in Working Generation Healthy Japanese Men: Post-Hoc Testing of a Randomized Controlled Trial Araki, Risa Sasaki, Kazunori Onda, Hiroyuki Nakamura, Syunsuke Kassai, Masahiro Kaneko, Toshiyuki Isoda, Hiroko Hashimoto, Koichi Nutrients Article We previously performed a 4 week interventional trial that suggested that continuous intake of rosemary extract improves the mood states, fatigue, and cognitive function of working generation healthy adult Japanese men. However, the severity of depression in participants in our previous study was relatively mild. Therefore, in the present study, a post-hoc analysis of our previous study was conducted, limited to participants whose total mood disturbance (TMD) scores, which indicate greater mood disturbance, were above the median at baseline, to evaluate whether rosemary extract was effective for individuals with poor mental health. Following the intervention, the scores of TMD and “Confusion-Bewilderment” were significantly decreased (both p < 0.05), and scores of “Vigor-Activity” were significantly increased in the rosemary group (n = 8) compared with those in the control group (n = 13; p < 0.01). When comparing the scores from pre- and post-intervention, significant improvements in “Tension-Anxiety”, “Vigor-Activity”, “Fatigue on awakening”, “Daytime sleepiness”, and “Psychomotor speed” were observed in the rosemary group only (all p < 0.05). Based on these results, it was expected that rosemary extracts were effective for improving the mental energy and sleep quality of work-age men with poor mental health. MDPI 2020-11-20 /pmc/articles/PMC7699484/ /pubmed/33233510 http://dx.doi.org/10.3390/nu12113551 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Araki, Risa
Sasaki, Kazunori
Onda, Hiroyuki
Nakamura, Syunsuke
Kassai, Masahiro
Kaneko, Toshiyuki
Isoda, Hiroko
Hashimoto, Koichi
Effects of Continuous Intake of Rosemary Extracts on Mental Health in Working Generation Healthy Japanese Men: Post-Hoc Testing of a Randomized Controlled Trial
title Effects of Continuous Intake of Rosemary Extracts on Mental Health in Working Generation Healthy Japanese Men: Post-Hoc Testing of a Randomized Controlled Trial
title_full Effects of Continuous Intake of Rosemary Extracts on Mental Health in Working Generation Healthy Japanese Men: Post-Hoc Testing of a Randomized Controlled Trial
title_fullStr Effects of Continuous Intake of Rosemary Extracts on Mental Health in Working Generation Healthy Japanese Men: Post-Hoc Testing of a Randomized Controlled Trial
title_full_unstemmed Effects of Continuous Intake of Rosemary Extracts on Mental Health in Working Generation Healthy Japanese Men: Post-Hoc Testing of a Randomized Controlled Trial
title_short Effects of Continuous Intake of Rosemary Extracts on Mental Health in Working Generation Healthy Japanese Men: Post-Hoc Testing of a Randomized Controlled Trial
title_sort effects of continuous intake of rosemary extracts on mental health in working generation healthy japanese men: post-hoc testing of a randomized controlled trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699484/
https://www.ncbi.nlm.nih.gov/pubmed/33233510
http://dx.doi.org/10.3390/nu12113551
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