Candidate Gene Discovery in Hereditary Colorectal Cancer and Polyposis Syndromes–Considerations for Future Studies

To discover novel high-penetrant risk loci for hereditary colorectal cancer (hCRC) and polyposis syndromes many whole-exome and whole-genome sequencing (WES/WGS) studies have been performed. Remarkably, these studies resulted in only a few novel high-penetrant risk genes. Given this observation, the...

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Detalles Bibliográficos
Autores principales: te Paske, Iris B. A. W., Ligtenberg, Marjolijn J. L., Hoogerbrugge, Nicoline, de Voer, Richarda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699508/
https://www.ncbi.nlm.nih.gov/pubmed/33228212
http://dx.doi.org/10.3390/ijms21228757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699508/
https://www.ncbi.nlm.nih.gov/pubmed/33228212
http://dx.doi.org/10.3390/ijms21228757

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