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Candidate Gene Discovery in Hereditary Colorectal Cancer and Polyposis Syndromes–Considerations for Future Studies

To discover novel high-penetrant risk loci for hereditary colorectal cancer (hCRC) and polyposis syndromes many whole-exome and whole-genome sequencing (WES/WGS) studies have been performed. Remarkably, these studies resulted in only a few novel high-penetrant risk genes. Given this observation, the...

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Detalles Bibliográficos
Autores principales:	te Paske, Iris B. A. W., Ligtenberg, Marjolijn J. L., Hoogerbrugge, Nicoline, de Voer, Richarda M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699508/ https://www.ncbi.nlm.nih.gov/pubmed/33228212 http://dx.doi.org/10.3390/ijms21228757

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