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COVID-19 as a Trigger of Recurrent Guillain–Barré Syndrome
Coronavirus 2019 (COVID-19) has been reported to trigger Guillain–Barré syndrome (GBS). While uncommon, recurrent GBS (rGBS) episodes, triggered by antecedent viral infections, have been reported in a small proportion of GBS patients, here we describe a patient with a recurrent case of GBS, occurrin...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699516/ https://www.ncbi.nlm.nih.gov/pubmed/33228253 http://dx.doi.org/10.3390/pathogens9110965 |
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author | McDonnell, Erin P. Altomare, Nicole J. Parekh, Yesha H. Gowda, Ram C. Parikh, Payal D. Lazar, Mark H. Blaser, Martin J. |
author_facet | McDonnell, Erin P. Altomare, Nicole J. Parekh, Yesha H. Gowda, Ram C. Parikh, Payal D. Lazar, Mark H. Blaser, Martin J. |
author_sort | McDonnell, Erin P. |
collection | PubMed |
description | Coronavirus 2019 (COVID-19) has been reported to trigger Guillain–Barré syndrome (GBS). While uncommon, recurrent GBS (rGBS) episodes, triggered by antecedent viral infections, have been reported in a small proportion of GBS patients, here we describe a patient with a recurrent case of GBS, occurring secondary to COVID-19 infection. Before this patient’s episode, he had two prior GBS flares, each precipitated by a viral infection followed by complete recovery besides intermittent paresthesias. We also consider the nosology of this illness in the spectrum of rGBS and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), with their differing natural histories, prognosis, and therapeutic approaches. For patients who have a history of inflammatory demyelinating polyradiculopathies who develop COVID-19, we recommend close observation for neurologic symptoms over the next days and weeks. |
format | Online Article Text |
id | pubmed-7699516 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76995162020-11-29 COVID-19 as a Trigger of Recurrent Guillain–Barré Syndrome McDonnell, Erin P. Altomare, Nicole J. Parekh, Yesha H. Gowda, Ram C. Parikh, Payal D. Lazar, Mark H. Blaser, Martin J. Pathogens Case Report Coronavirus 2019 (COVID-19) has been reported to trigger Guillain–Barré syndrome (GBS). While uncommon, recurrent GBS (rGBS) episodes, triggered by antecedent viral infections, have been reported in a small proportion of GBS patients, here we describe a patient with a recurrent case of GBS, occurring secondary to COVID-19 infection. Before this patient’s episode, he had two prior GBS flares, each precipitated by a viral infection followed by complete recovery besides intermittent paresthesias. We also consider the nosology of this illness in the spectrum of rGBS and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), with their differing natural histories, prognosis, and therapeutic approaches. For patients who have a history of inflammatory demyelinating polyradiculopathies who develop COVID-19, we recommend close observation for neurologic symptoms over the next days and weeks. MDPI 2020-11-19 /pmc/articles/PMC7699516/ /pubmed/33228253 http://dx.doi.org/10.3390/pathogens9110965 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report McDonnell, Erin P. Altomare, Nicole J. Parekh, Yesha H. Gowda, Ram C. Parikh, Payal D. Lazar, Mark H. Blaser, Martin J. COVID-19 as a Trigger of Recurrent Guillain–Barré Syndrome |
title | COVID-19 as a Trigger of Recurrent Guillain–Barré Syndrome |
title_full | COVID-19 as a Trigger of Recurrent Guillain–Barré Syndrome |
title_fullStr | COVID-19 as a Trigger of Recurrent Guillain–Barré Syndrome |
title_full_unstemmed | COVID-19 as a Trigger of Recurrent Guillain–Barré Syndrome |
title_short | COVID-19 as a Trigger of Recurrent Guillain–Barré Syndrome |
title_sort | covid-19 as a trigger of recurrent guillain–barré syndrome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699516/ https://www.ncbi.nlm.nih.gov/pubmed/33228253 http://dx.doi.org/10.3390/pathogens9110965 |
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