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Immunoprofiling in Neuroendocrine Neoplasms Unveil Immunosuppressive Microenvironment

SIMPLE SUMMARY: Immunotherapy with checkpoint inhibitors targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) axis or Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) has shown only modest activity in neuroendocrine tumors (NET) and neuroendocrine carcinomas (NE...

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Detalles Bibliográficos
Autores principales: Busse, Antonia, Mochmann, Liliana H., Spenke, Christiane, Arsenic, Ruza, Briest, Franziska, Jöhrens, Korinna, Lammert, Hedwig, Sipos, Bence, Kühl, Anja A., Wirtz, Ralph, Pavel, Marianne, Hummel, Michael, Kaemmerer, Daniel, Baum, Richard P., Grabowski, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699546/
https://www.ncbi.nlm.nih.gov/pubmed/33228231
http://dx.doi.org/10.3390/cancers12113448