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Comprehensive prediction of secondary metabolite structure and biological activity from microbial genome sequences

Novel antibiotics are urgently needed to address the looming global crisis of antibiotic resistance. Historically, the primary source of clinically used antibiotics has been microbial secondary metabolism. Microbial genome sequencing has revealed a plethora of uncharacterized natural antibiotics tha...

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Detalles Bibliográficos
Autores principales:	Skinnider, Michael A., Johnston, Chad W., Gunabalasingam, Mathusan, Merwin, Nishanth J., Kieliszek, Agata M., MacLellan, Robyn J., Li, Haoxin, Ranieri, Michael R. M., Webster, Andrew L. H., Cao, My P. T., Pfeifle, Annabelle, Spencer, Norman, To, Q. Huy, Wallace, Dan Peter, Dejong, Chris A., Magarvey, Nathan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699628/ https://www.ncbi.nlm.nih.gov/pubmed/33247171 http://dx.doi.org/10.1038/s41467-020-19986-1

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