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Ligand-induced conformational rearrangements regulate the switch between membrane-proximal and distal functions of Rho kinase 2
Rho-associated protein kinase 2 (ROCK2) is a membrane-anchored, long, flexible, multidomain, multifunctional protein. Its functions can be divided into two categories: membrane-proximal and membrane-distal. A recent study concluded that membrane-distal functions require the fully extended conformati...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699638/ https://www.ncbi.nlm.nih.gov/pubmed/33247217 http://dx.doi.org/10.1038/s42003-020-01450-x |