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Lagged Association of Ambient Outdoor Air Pollutants with Asthma-Related Emergency Department Visits within the Pittsburgh Region
Asthma affects millions of people globally and is especially concerning in populations living with poor air quality. This study examines the association of ambient outdoor air pollutants on asthma-related emergency department (ED) visits in children and adults throughout the Pittsburgh region. A tim...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699695/ https://www.ncbi.nlm.nih.gov/pubmed/33233547 http://dx.doi.org/10.3390/ijerph17228619 |
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author | Byrwa-Hill, Brandy M. Venkat, Arvind Presto, Albert A. Rager, Judith R. Gentile, Deborah Talbott, Evelyn |
author_facet | Byrwa-Hill, Brandy M. Venkat, Arvind Presto, Albert A. Rager, Judith R. Gentile, Deborah Talbott, Evelyn |
author_sort | Byrwa-Hill, Brandy M. |
collection | PubMed |
description | Asthma affects millions of people globally and is especially concerning in populations living with poor air quality. This study examines the association of ambient outdoor air pollutants on asthma-related emergency department (ED) visits in children and adults throughout the Pittsburgh region. A time-stratified case-crossover design is used to analyze the lagged effects of fine particulate matter (PM(2.5)) and gaseous pollutants, e.g., ozone (O(3)), sulfur dioxide (SO(2)), nitrogen dioxide (NO(2)), and carbon monoxide (CO) on asthma-related ED visits (n = 6682). Single-, double-, and multi-pollutant models are adjusted for temperature and analyzed using conditional logistic regression. In children, all models show an association between O(3) and increased ED visits at lag day 1 (OR: 1.12, 95% CI, 1.03–1.22, p < 0.05) for the double-pollutant model (OR: 1.10, 95% CI: 1.01-1.20, p < 0.01). In adults, the single-pollutant model shows associations between CO and increased ED visits at lag day 5 (OR: 1.13, 95% CI, 1.00–1.28, p < 0.05) and average lag days 0–5 (OR: 1.22, 95% CI: 1.00–1.49, p < 0.05), and for NO(2) at lag day 5 (OR: 1.04, 95% CI: 1.00–1.07, p < 0.05). These results show an association between air pollution and asthma morbidity in the Pittsburgh region and underscore the need for mitigation efforts to improve public health outcomes. |
format | Online Article Text |
id | pubmed-7699695 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76996952020-11-29 Lagged Association of Ambient Outdoor Air Pollutants with Asthma-Related Emergency Department Visits within the Pittsburgh Region Byrwa-Hill, Brandy M. Venkat, Arvind Presto, Albert A. Rager, Judith R. Gentile, Deborah Talbott, Evelyn Int J Environ Res Public Health Article Asthma affects millions of people globally and is especially concerning in populations living with poor air quality. This study examines the association of ambient outdoor air pollutants on asthma-related emergency department (ED) visits in children and adults throughout the Pittsburgh region. A time-stratified case-crossover design is used to analyze the lagged effects of fine particulate matter (PM(2.5)) and gaseous pollutants, e.g., ozone (O(3)), sulfur dioxide (SO(2)), nitrogen dioxide (NO(2)), and carbon monoxide (CO) on asthma-related ED visits (n = 6682). Single-, double-, and multi-pollutant models are adjusted for temperature and analyzed using conditional logistic regression. In children, all models show an association between O(3) and increased ED visits at lag day 1 (OR: 1.12, 95% CI, 1.03–1.22, p < 0.05) for the double-pollutant model (OR: 1.10, 95% CI: 1.01-1.20, p < 0.01). In adults, the single-pollutant model shows associations between CO and increased ED visits at lag day 5 (OR: 1.13, 95% CI, 1.00–1.28, p < 0.05) and average lag days 0–5 (OR: 1.22, 95% CI: 1.00–1.49, p < 0.05), and for NO(2) at lag day 5 (OR: 1.04, 95% CI: 1.00–1.07, p < 0.05). These results show an association between air pollution and asthma morbidity in the Pittsburgh region and underscore the need for mitigation efforts to improve public health outcomes. MDPI 2020-11-20 2020-11 /pmc/articles/PMC7699695/ /pubmed/33233547 http://dx.doi.org/10.3390/ijerph17228619 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Byrwa-Hill, Brandy M. Venkat, Arvind Presto, Albert A. Rager, Judith R. Gentile, Deborah Talbott, Evelyn Lagged Association of Ambient Outdoor Air Pollutants with Asthma-Related Emergency Department Visits within the Pittsburgh Region |
title | Lagged Association of Ambient Outdoor Air Pollutants with Asthma-Related Emergency Department Visits within the Pittsburgh Region |
title_full | Lagged Association of Ambient Outdoor Air Pollutants with Asthma-Related Emergency Department Visits within the Pittsburgh Region |
title_fullStr | Lagged Association of Ambient Outdoor Air Pollutants with Asthma-Related Emergency Department Visits within the Pittsburgh Region |
title_full_unstemmed | Lagged Association of Ambient Outdoor Air Pollutants with Asthma-Related Emergency Department Visits within the Pittsburgh Region |
title_short | Lagged Association of Ambient Outdoor Air Pollutants with Asthma-Related Emergency Department Visits within the Pittsburgh Region |
title_sort | lagged association of ambient outdoor air pollutants with asthma-related emergency department visits within the pittsburgh region |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699695/ https://www.ncbi.nlm.nih.gov/pubmed/33233547 http://dx.doi.org/10.3390/ijerph17228619 |
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