Cargando…
Responses of DNA Mismatch Repair Proteins to a Stable G-Quadruplex Embedded into a DNA Duplex Structure
DNA mismatch repair (MMR) plays a crucial role in the maintenance of genomic stability. The main MMR protein, MutS, was recently shown to recognize the G-quadruplex (G4) DNA structures, which, along with regulatory functions, have a negative impact on genome integrity. Here, we studied the effect of...
Autores principales: | Pavlova, Anzhela V., Monakhova, Mayya V., Ogloblina, Anna M., Andreeva, Natalia A., Laptev, Gennady Yu., Polshakov, Vladimir I., Gromova, Elizaveta S., Zvereva, Maria I., Yakubovskaya, Marianna G., Oretskaya, Tatiana S., Kubareva, Elena A., Dolinnaya, Nina G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699706/ https://www.ncbi.nlm.nih.gov/pubmed/33233554 http://dx.doi.org/10.3390/ijms21228773 |
Ejemplares similares
-
Impact of G-Quadruplexes on the Regulation of Genome Integrity, DNA Damage and Repair
por: Pavlova, Anzhela V., et al.
Publicado: (2021) -
New DNA Plasmid Model for Studying DNA Mismatch Repair Response to the G4 Structure
por: Pavlova, Anzhela V., et al.
Publicado: (2023) -
G-Quadruplex Formed by the Promoter Region of the hTERT Gene: Structure-Driven Effects on DNA Mismatch Repair Functions
por: Pavlova, Anzhela V., et al.
Publicado: (2022) -
Impact of G-Quadruplex Structures on Methylation of Model Substrates by DNA Methyltransferase Dnmt3a
por: Loiko, Andrei G., et al.
Publicado: (2022) -
Structure, properties, and biological relevance of the DNA and RNA G-quadruplexes: Overview 50 years after their discovery
por: Dolinnaya, N. G., et al.
Publicado: (2017)