Cargando…
Inhibitory Effect of Lithospermic Acid on the HIV-1 Nucleocapsid Protein
The HIV-1 nucleocapsid protein (NC) is a desirable target in antiretroviral therapy due to its high conservation among HIV-1 strains, and to its multiple and crucial roles in the HIV-1 replication cycle. Natural products represent a valuable source of NC inhibitors, with the catechol group being a p...
Autores principales: | Mori, Mattia, Ciaco, Stefano, Mély, Yves, Karioti, Anastasia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699738/ https://www.ncbi.nlm.nih.gov/pubmed/33233563 http://dx.doi.org/10.3390/molecules25225434 |
Ejemplares similares
-
Nucleocapsid Protein: A Desirable Target for Future Therapies Against HIV-1
por: Mori, Mattia, et al.
Publicado: (2015) -
Comparative nucleic acid chaperone properties of the nucleocapsid protein NCp7 and Tat protein of HIV-1
por: Godet, Julien, et al.
Publicado: (2012) -
Intrinsic Nucleic Acid Dynamics Modulates HIV-1 Nucleocapsid Protein Binding to Its Targets
por: Bazzi, Ali, et al.
Publicado: (2012) -
FRET-based assay to screen inhibitors of HIV-1 reverse transcriptase and nucleocapsid protein
por: Sharma, Kamal K., et al.
Publicado: (2016) -
Dynamics of Linker Residues Modulate the Nucleic Acid Binding Properties of the HIV-1 Nucleocapsid Protein Zinc Fingers
por: Zargarian, Loussiné, et al.
Publicado: (2014)