The Proteasome Activators Blm10/PA200 Enhance the Proteasomal Degradation of N-Terminal Huntingtin

The Blm10/PA200 family of proteasome activators modulates the peptidase activity of the core particle (20S CP). They participate in opening the 20S CP gate, thus facilitating the degradation of unstructured proteins such as tau and Dnm1 in a ubiquitin- and ATP-independent manner. Furthermore, PA200...

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Detalles Bibliográficos
Autores principales: Aladdin, Azzam, Yao, Yanhua, Yang, Ciyu, Kahlert, Günther, Ghani, Marvi, Király, Nikolett, Boratkó, Anita, Uray, Karen, Dittmar, Gunnar, Tar, Krisztina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699873/
https://www.ncbi.nlm.nih.gov/pubmed/33233776
http://dx.doi.org/10.3390/biom10111581

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