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Carvedilol, an Adrenergic Blocker, Suppresses Melanin Synthesis by Inhibiting the cAMP/CREB Signaling Pathway in Human Melanocytes and Ex Vivo Human Skin Culture

Catecholamines function via G protein-coupled receptors, triggering an increase in intracellular levels of 3′,5′-cyclic adenosine monophosphate (cAMP) in various cells. Catecholamine biosynthesis and the β-adrenergic receptor exist in melanocytes; thus, catecholamines may play critical roles in skin...

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Detalles Bibliográficos
Autores principales:	Choi, Myoung Eun, Yoo, Hanju, Lee, Ha-Ri, Moon, Ik Joon, Lee, Woo Jin, Song, Youngsup, Chang, Sung Eun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699935/ https://www.ncbi.nlm.nih.gov/pubmed/33233731 http://dx.doi.org/10.3390/ijms21228796

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