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Currently Applied Molecular Assays for Identifying ESR1 Mutations in Patients with Advanced Breast Cancer

Approximately 70% of breast cancers, the leading cause of cancer-related mortality worldwide, are positive for the estrogen receptor (ER). Treatment of patients with luminal subtypes is mainly based on endocrine therapy. However, ER positivity is reduced and ESR1 mutations play an important role in...

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Detalles Bibliográficos
Autores principales: Lee, Nuri, Park, Min-Jeong, Song, Wonkeun, Jeon, Kibum, Jeong, Seri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699999/
https://www.ncbi.nlm.nih.gov/pubmed/33233830
http://dx.doi.org/10.3390/ijms21228807