Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2

BACKGROUND: SARS-CoV-2 is the virus responsible for the current global pandemic, COVID-19. Because this virus is novel, little is known about its sensitivity to disinfection. METHODS: We performed suspension tests against SARS-CoV-2 using three commercially available quaternary ammonium compound (Qu...

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Detalles Bibliográficos
Autores principales: Ogilvie, B.H., Solis-Leal, A., Lopez, J.B., Poole, B.D., Robison, R.A., Berges, B.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd on behalf of The Healthcare Infection Society. 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700010/
https://www.ncbi.nlm.nih.gov/pubmed/33259880
http://dx.doi.org/10.1016/j.jhin.2020.11.023
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author Ogilvie, B.H.
Solis-Leal, A.
Lopez, J.B.
Poole, B.D.
Robison, R.A.
Berges, B.K.
author_facet Ogilvie, B.H.
Solis-Leal, A.
Lopez, J.B.
Poole, B.D.
Robison, R.A.
Berges, B.K.
author_sort Ogilvie, B.H.
collection PubMed
description BACKGROUND: SARS-CoV-2 is the virus responsible for the current global pandemic, COVID-19. Because this virus is novel, little is known about its sensitivity to disinfection. METHODS: We performed suspension tests against SARS-CoV-2 using three commercially available quaternary ammonium compound (Quat) disinfectants and one laboratory-made 0.2% benzalkonium chloride solution. FINDINGS: Three of the four formulations completely inactivated the virus within 15 s of contact, even in the presence of a soil load or when diluted in hard water. CONCLUSION: Quats rapidly inactivate SARS-CoV-2, making them potentially useful for controlling SARS-CoV-2 spread in hospitals and the community.
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spelling pubmed-77000102020-12-01 Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2 Ogilvie, B.H. Solis-Leal, A. Lopez, J.B. Poole, B.D. Robison, R.A. Berges, B.K. J Hosp Infect Short Report BACKGROUND: SARS-CoV-2 is the virus responsible for the current global pandemic, COVID-19. Because this virus is novel, little is known about its sensitivity to disinfection. METHODS: We performed suspension tests against SARS-CoV-2 using three commercially available quaternary ammonium compound (Quat) disinfectants and one laboratory-made 0.2% benzalkonium chloride solution. FINDINGS: Three of the four formulations completely inactivated the virus within 15 s of contact, even in the presence of a soil load or when diluted in hard water. CONCLUSION: Quats rapidly inactivate SARS-CoV-2, making them potentially useful for controlling SARS-CoV-2 spread in hospitals and the community. The Authors. Published by Elsevier Ltd on behalf of The Healthcare Infection Society. 2021-02 2020-11-28 /pmc/articles/PMC7700010/ /pubmed/33259880 http://dx.doi.org/10.1016/j.jhin.2020.11.023 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Report
Ogilvie, B.H.
Solis-Leal, A.
Lopez, J.B.
Poole, B.D.
Robison, R.A.
Berges, B.K.
Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2
title Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2
title_full Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2
title_fullStr Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2
title_full_unstemmed Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2
title_short Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2
title_sort alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate sars-cov-2
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700010/
https://www.ncbi.nlm.nih.gov/pubmed/33259880
http://dx.doi.org/10.1016/j.jhin.2020.11.023
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