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Quinovic Acid Impedes Cholesterol Dyshomeostasis, Oxidative Stress, and Neurodegeneration in an Amyloid-β-Induced Mouse Model
Alzheimer's disease (AD) is a progressive neurodegenerative disorder typified by several neuropathological features including amyloid-beta (Aβ) plaque and neurofibrillary tangles (NFTs). Cholesterol retention and oxidative stress (OS) are the major contributors of elevated β- and γ-secretase ac...
Autores principales: | Saeed, Kamran, Shah, Shahid Ali, Ullah, Rahat, Alam, Sayed Ibrar, Park, Jun Sung, Saleem, Samreen, Jo, Myeung Hoon, Kim, Min Woo, Hahm, Jong Ryeal, Kim, Myeong Ok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700034/ https://www.ncbi.nlm.nih.gov/pubmed/33274012 http://dx.doi.org/10.1155/2020/9523758 |
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