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Population Pharmacokinetics of Tapentadol in Children from Birth to <18 Years Old

OBJECTIVE: The main aim of this analysis was to characterize the pharmacokinetics (PK) of tapentadol in pediatric patients from birth to <18 years old who experience acute pain, requiring treatment with an opioid analgesic. PATIENTS AND METHODS: Data from four clinical trials and 148 pediatric pa...

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Detalles Bibliográficos
Autores principales: Khalil, Feras, Choi, Siak Leng, Watson, Estelle, Tzschentke, Thomas M, Lefeber, Claudia, Eerdekens, Mariëlle, Freijer, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700087/
https://www.ncbi.nlm.nih.gov/pubmed/33262645
http://dx.doi.org/10.2147/JPR.S269549