Cargando…
Addressing Latent Tuberculosis: New Advances in Mimicking the Disease, Discovering Key Targets, and Designing Hit Compounds
Despite being discovered and isolated more than one hundred years ago, tuberculosis (TB) remains a global public health concern arch. Our inability to eradicate this bacillus is strongly related with the growing resistance, low compliance to current drugs, and the capacity of the bacteria to coexist...
Autores principales: | Campaniço, André, Harjivan, Shrika G., Warner, Digby F., Moreira, Rui, Lopes, Francisca |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700174/ https://www.ncbi.nlm.nih.gov/pubmed/33238468 http://dx.doi.org/10.3390/ijms21228854 |
Ejemplares similares
-
Hit Compounds and Associated Targets in Intracellular Mycobacterium tuberculosis
por: Tsui, Clement K. M., et al.
Publicado: (2022) -
Biological Profiling Enables Rapid Mechanistic Classification of Phenotypic Screening Hits and Identification of KatG Activation-Dependent Pyridine Carboxamide Prodrugs With Activity Against Mycobacterium tuberculosis
por: Chengalroyen, Melissa D., et al.
Publicado: (2020) -
Hitting the bull’s eye of ending tuberculosis goal: The challenge of addressing tuberculosis in human immunodeficiency virus positive population in India
por: Dabla, Vandana
Publicado: (2019) -
Death of Mycobacterium tuberculosis by l-arginine starvation
por: Mizrahi, Valerie, et al.
Publicado: (2018) -
Novel Hits for N-Myristoyltransferase Inhibition Discovered by Docking-Based Screening
por: Spassov, Danislav S., et al.
Publicado: (2022)