Allyl Isothiocyanate Protects Acetaminophen-Induced Liver Injury via NRF2 Activation by Decreasing Spontaneous Degradation in Hepatocyte

Acetaminophen (APAP) is one of the most frequently prescribed analgesic and anti-pyretic drugs. However, APAP-induced hepatotoxicity is a major cause of acute liver failure globally. While the therapeutic dose is safe, an overdose of APAP produces an excess of the toxic metabolite N-acetyl-p-benzoqu...

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Detalles Bibliográficos
Autores principales: Kim, Min Woo, Kang, Ju-Hee, Jung, Hyun Jin, Park, Se Yong, Phan, Thu Han Le, Namgung, Hee, Seo, Seung-Yong, Yoon, Yeo Sung, Oh, Seung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700243/
https://www.ncbi.nlm.nih.gov/pubmed/33238403
http://dx.doi.org/10.3390/nu12113585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700243/
https://www.ncbi.nlm.nih.gov/pubmed/33238403
http://dx.doi.org/10.3390/nu12113585

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