Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFRα1 for Specific Infection of Breast Cancer Cells

Oncolytic herpes simplex viruses (oHSV) are under development for the treatment of a variety of human cancers, including breast cancer, a leading cause of cancer mortality among women worldwide. Here we report the design of a fully retargeted oHSV for preferential infection of breast cancer cells th...

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Detalles Bibliográficos
Autores principales: Hall, Bonnie L., Leronni, Daniela, Miyagawa, Yoshitaka, Goins, William F., Glorioso, Joseph C., Cohen, Justus B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700293/
https://www.ncbi.nlm.nih.gov/pubmed/33233403
http://dx.doi.org/10.3390/ijms21228815

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