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Synergy Effect of Combined Near and Mid-Infrared Fibre Spectroscopy for Diagnostics of Abdominal Cancer
Cancers of the abdominal cavity comprise one of the most prevalent forms of cancers, with the highest contribution from colon and rectal cancers (12% of the human population), followed by stomach cancers (4%). Surgery, as the preferred choice of treatment, includes the selection of adequate resectio...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700420/ https://www.ncbi.nlm.nih.gov/pubmed/33238646 http://dx.doi.org/10.3390/s20226706 |
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author | Hocotz, Thaddäus Bibikova, Olga Belikova, Valeria Bogomolov, Andrey Usenov, Iskander Pieszczek, Lukasz Sakharova, Tatiana Minet, Olaf Feliksberger, Elena Artyushenko, Viacheslav Rau, Beate Zabarylo, Urszula |
author_facet | Hocotz, Thaddäus Bibikova, Olga Belikova, Valeria Bogomolov, Andrey Usenov, Iskander Pieszczek, Lukasz Sakharova, Tatiana Minet, Olaf Feliksberger, Elena Artyushenko, Viacheslav Rau, Beate Zabarylo, Urszula |
author_sort | Hocotz, Thaddäus |
collection | PubMed |
description | Cancers of the abdominal cavity comprise one of the most prevalent forms of cancers, with the highest contribution from colon and rectal cancers (12% of the human population), followed by stomach cancers (4%). Surgery, as the preferred choice of treatment, includes the selection of adequate resection margins to avoid local recurrences due to minimal residual disease. The presence of functionally vital structures can complicate the choice of resection margins. Spectral analysis of tissue samples in combination with chemometric models constitutes a promising approach for more efficient and precise tumour margin identification. Additionally, this technique provides a real-time tumour identification approach not only for intraoperative application but also during endoscopic diagnosis of tumours in hollow organs. The combination of near-infrared and mid-infrared spectroscopy has advantages compared to individual methods for the clinical implementation of this technique as a diagnostic tool. |
format | Online Article Text |
id | pubmed-7700420 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-77004202020-11-30 Synergy Effect of Combined Near and Mid-Infrared Fibre Spectroscopy for Diagnostics of Abdominal Cancer Hocotz, Thaddäus Bibikova, Olga Belikova, Valeria Bogomolov, Andrey Usenov, Iskander Pieszczek, Lukasz Sakharova, Tatiana Minet, Olaf Feliksberger, Elena Artyushenko, Viacheslav Rau, Beate Zabarylo, Urszula Sensors (Basel) Article Cancers of the abdominal cavity comprise one of the most prevalent forms of cancers, with the highest contribution from colon and rectal cancers (12% of the human population), followed by stomach cancers (4%). Surgery, as the preferred choice of treatment, includes the selection of adequate resection margins to avoid local recurrences due to minimal residual disease. The presence of functionally vital structures can complicate the choice of resection margins. Spectral analysis of tissue samples in combination with chemometric models constitutes a promising approach for more efficient and precise tumour margin identification. Additionally, this technique provides a real-time tumour identification approach not only for intraoperative application but also during endoscopic diagnosis of tumours in hollow organs. The combination of near-infrared and mid-infrared spectroscopy has advantages compared to individual methods for the clinical implementation of this technique as a diagnostic tool. MDPI 2020-11-23 /pmc/articles/PMC7700420/ /pubmed/33238646 http://dx.doi.org/10.3390/s20226706 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Hocotz, Thaddäus Bibikova, Olga Belikova, Valeria Bogomolov, Andrey Usenov, Iskander Pieszczek, Lukasz Sakharova, Tatiana Minet, Olaf Feliksberger, Elena Artyushenko, Viacheslav Rau, Beate Zabarylo, Urszula Synergy Effect of Combined Near and Mid-Infrared Fibre Spectroscopy for Diagnostics of Abdominal Cancer |
title | Synergy Effect of Combined Near and Mid-Infrared Fibre Spectroscopy for Diagnostics of Abdominal Cancer |
title_full | Synergy Effect of Combined Near and Mid-Infrared Fibre Spectroscopy for Diagnostics of Abdominal Cancer |
title_fullStr | Synergy Effect of Combined Near and Mid-Infrared Fibre Spectroscopy for Diagnostics of Abdominal Cancer |
title_full_unstemmed | Synergy Effect of Combined Near and Mid-Infrared Fibre Spectroscopy for Diagnostics of Abdominal Cancer |
title_short | Synergy Effect of Combined Near and Mid-Infrared Fibre Spectroscopy for Diagnostics of Abdominal Cancer |
title_sort | synergy effect of combined near and mid-infrared fibre spectroscopy for diagnostics of abdominal cancer |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700420/ https://www.ncbi.nlm.nih.gov/pubmed/33238646 http://dx.doi.org/10.3390/s20226706 |
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