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The Intergenerational Transmission of Chronic Pain from Parents to Survivors of Childhood Cancer

Background: Among youth with chronic non-cancer pain, 50% have parents with chronic pain. These youth report significantly more pain interference and posttraumatic stress symptoms (PTSS), and worse health-related quality of life (HRQL) than youth whose parents do not have chronic pain. Additionally,...

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Autores principales: Patton, Michaela, Stokoe, Mehak, Forbes, Caitlin, Nwaroh, Chidera, Noel, Melanie, Reynolds, Kathleen, Schulte, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700439/
https://www.ncbi.nlm.nih.gov/pubmed/33233437
http://dx.doi.org/10.3390/children7110246
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author Patton, Michaela
Stokoe, Mehak
Forbes, Caitlin
Nwaroh, Chidera
Noel, Melanie
Reynolds, Kathleen
Schulte, Fiona
author_facet Patton, Michaela
Stokoe, Mehak
Forbes, Caitlin
Nwaroh, Chidera
Noel, Melanie
Reynolds, Kathleen
Schulte, Fiona
author_sort Patton, Michaela
collection PubMed
description Background: Among youth with chronic non-cancer pain, 50% have parents with chronic pain. These youth report significantly more pain interference and posttraumatic stress symptoms (PTSS), and worse health-related quality of life (HRQL) than youth whose parents do not have chronic pain. Additionally, parent chronic pain is linked to increased child anxiety and depressive symptoms. Survivors of childhood cancer (SCCs) are at risk of pain and negative psychosocial outcomes and therefore may be especially vulnerable if their parents have chronic pain. Thus, the aims of the current study were to (1) identify rates of chronic pain among parents of SCCs, (2) test group differences in psychological symptoms in parents with chronic pain versus without, and (3) test group differences in pain interference, HRQL, anxiety, depression, and PTSS in SCCs with parents with chronic pain versus without. Methods: 122 SCCs (Mean age = 15.8, SD = 4.8, 45.7% male, Mean age at diagnosis = 5.9, SD = 4.7) and their parents were recruited from across Canada to complete online questionnaires. Parents were asked if they have had pain for at least three consecutive months and completed the brief symptom inventory (BSI) as a measure of psychological symptomatology. Survivors completed the pain questionnaire, patient reported outcomes measurement information system (PROMIS)—pain interference, anxiety, and depression measures, child posttraumatic stress scale, posttraumatic stress disorder checklist for the Diagnostic and Statistical Manual of Mental Disorders, and the pediatric quality of life inventory. Results: Forty-three (39%) parents of SCCs reported having chronic pain. Of the 29 survivors who had chronic pain, 14 (48%) also had parents with chronic pain. Parents with chronic pain reported significantly higher scores on the BSI than parents without chronic pain, F(1, 116) = 5.07, p = 0.026. SCCs with parents with versus without chronic pain reported significantly higher PTSS F(1, 105) = 10.53, p = 0.002 and depressive symptoms F(1, 102) = 6.68, p = 0.011. No significant differences were found across the other variables tested. Conclusions: Findings suggest that survivors’ parents’ own pain is prevalent and is related to survivors’ increased depressive symptoms and PTSS, but not anxiety, pain interference, or HRQL. Future research should explore whether parents may benefit from psychological intervention after their child has been diagnosed with cancer and how this could improve outcomes for their child.
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spelling pubmed-77004392020-11-30 The Intergenerational Transmission of Chronic Pain from Parents to Survivors of Childhood Cancer Patton, Michaela Stokoe, Mehak Forbes, Caitlin Nwaroh, Chidera Noel, Melanie Reynolds, Kathleen Schulte, Fiona Children (Basel) Article Background: Among youth with chronic non-cancer pain, 50% have parents with chronic pain. These youth report significantly more pain interference and posttraumatic stress symptoms (PTSS), and worse health-related quality of life (HRQL) than youth whose parents do not have chronic pain. Additionally, parent chronic pain is linked to increased child anxiety and depressive symptoms. Survivors of childhood cancer (SCCs) are at risk of pain and negative psychosocial outcomes and therefore may be especially vulnerable if their parents have chronic pain. Thus, the aims of the current study were to (1) identify rates of chronic pain among parents of SCCs, (2) test group differences in psychological symptoms in parents with chronic pain versus without, and (3) test group differences in pain interference, HRQL, anxiety, depression, and PTSS in SCCs with parents with chronic pain versus without. Methods: 122 SCCs (Mean age = 15.8, SD = 4.8, 45.7% male, Mean age at diagnosis = 5.9, SD = 4.7) and their parents were recruited from across Canada to complete online questionnaires. Parents were asked if they have had pain for at least three consecutive months and completed the brief symptom inventory (BSI) as a measure of psychological symptomatology. Survivors completed the pain questionnaire, patient reported outcomes measurement information system (PROMIS)—pain interference, anxiety, and depression measures, child posttraumatic stress scale, posttraumatic stress disorder checklist for the Diagnostic and Statistical Manual of Mental Disorders, and the pediatric quality of life inventory. Results: Forty-three (39%) parents of SCCs reported having chronic pain. Of the 29 survivors who had chronic pain, 14 (48%) also had parents with chronic pain. Parents with chronic pain reported significantly higher scores on the BSI than parents without chronic pain, F(1, 116) = 5.07, p = 0.026. SCCs with parents with versus without chronic pain reported significantly higher PTSS F(1, 105) = 10.53, p = 0.002 and depressive symptoms F(1, 102) = 6.68, p = 0.011. No significant differences were found across the other variables tested. Conclusions: Findings suggest that survivors’ parents’ own pain is prevalent and is related to survivors’ increased depressive symptoms and PTSS, but not anxiety, pain interference, or HRQL. Future research should explore whether parents may benefit from psychological intervention after their child has been diagnosed with cancer and how this could improve outcomes for their child. MDPI 2020-11-21 /pmc/articles/PMC7700439/ /pubmed/33233437 http://dx.doi.org/10.3390/children7110246 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Patton, Michaela
Stokoe, Mehak
Forbes, Caitlin
Nwaroh, Chidera
Noel, Melanie
Reynolds, Kathleen
Schulte, Fiona
The Intergenerational Transmission of Chronic Pain from Parents to Survivors of Childhood Cancer
title The Intergenerational Transmission of Chronic Pain from Parents to Survivors of Childhood Cancer
title_full The Intergenerational Transmission of Chronic Pain from Parents to Survivors of Childhood Cancer
title_fullStr The Intergenerational Transmission of Chronic Pain from Parents to Survivors of Childhood Cancer
title_full_unstemmed The Intergenerational Transmission of Chronic Pain from Parents to Survivors of Childhood Cancer
title_short The Intergenerational Transmission of Chronic Pain from Parents to Survivors of Childhood Cancer
title_sort intergenerational transmission of chronic pain from parents to survivors of childhood cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700439/
https://www.ncbi.nlm.nih.gov/pubmed/33233437
http://dx.doi.org/10.3390/children7110246
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