Cargando…
CRISPR FokI Dead Cas9 System: Principles and Applications in Genome Engineering
The identification of the robust clustered regularly interspersed short palindromic repeats (CRISPR) associated endonuclease (Cas9) system gene-editing tool has opened up a wide range of potential therapeutic applications that were restricted by more complex tools, including zinc finger nucleases (Z...
Autores principales: | Saifaldeen, Maryam, Al-Ansari, Dana E., Ramotar, Dindial, Aouida, Mustapha |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700487/ https://www.ncbi.nlm.nih.gov/pubmed/33233344 http://dx.doi.org/10.3390/cells9112518 |
Ejemplares similares
-
A CRISPR-based approach using dead Cas9-sgRNA to detect SARS-CoV-2
por: Aouida, Mustapha, et al.
Publicado: (2023) -
A simple protocol to isolate a single human cell PRDX1 knockout generated by CRISPR-Cas9 system
por: Aouida, Mustapha, et al.
Publicado: (2022) -
Generation of mutant mice via the CRISPR/Cas9 system using FokI-dCas9
por: Hara, Satoshi, et al.
Publicado: (2015) -
Utilization of the CRISPR/Cas9 system for the efficient production of mutant
mice using crRNA/tracrRNA with Cas9 nickase and FokI-dCas9
por: Terao, Miho, et al.
Publicado: (2016) -
Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
por: Tsai, Shengdar Q., et al.
Publicado: (2014)