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Modified Clavien–Dindo Classification and Outcome Prediction in Free Flap Reconstruction among Patients with Head and Neck Cancer
Because of limitations caused by unique complications of free flap reconstruction, the Clavien–Dindo classification was modified to include grade “IIIc” for “partial or total free flap failure.” From 2013 to 2018, 116 patients who had undergone free flap reconstruction for head and neck cancer with...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700532/ https://www.ncbi.nlm.nih.gov/pubmed/33266480 http://dx.doi.org/10.3390/jcm9113770 |
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author | Jan, Wei-Ling Chen, Hung-Chi Chang, Chang-Cheng Chen, Hsin-Han Shih, Pin-Keng Huang, Tsung-Chun |
author_facet | Jan, Wei-Ling Chen, Hung-Chi Chang, Chang-Cheng Chen, Hsin-Han Shih, Pin-Keng Huang, Tsung-Chun |
author_sort | Jan, Wei-Ling |
collection | PubMed |
description | Because of limitations caused by unique complications of free flap reconstruction, the Clavien–Dindo classification was modified to include grade “IIIc” for “partial or total free flap failure.” From 2013 to 2018, 116 patients who had undergone free flap reconstruction for head and neck cancer with grade III or higher postoperative complications were grouped using the “Modified” Clavien–Dindo classification. Alcoholism displayed significant predictive effects between grade IIIb and IIIc (72.7% vs. 50%, p = 0.028). Significant differences were observed between grade IIIb and IIIc in the duration of hospital stay (23.1 ± 10.1 vs. 28.6 ± 11.9 days, p = 0.015), duration of intensive care unit stay (6.0 ± 3.4 vs. 8.7 ± 4.3 days, p = 0.001), reoperation times during the current hospitalization (1.4 ± 0.8 vs. 2.0 ± 1.0 times, p < 0.001), and wound infection rate (29.9% vs. 62.5%, p = 0.002). The severity levels were significantly positively correlated with reoperation times during the current hospitalization (p < 0.001), ICU stay (p = 0.001), and hospital stay (p < 0.001). The modified Clavien–Dindo classification with grade IIIc describes the perioperative complications of head and neck free flap reconstruction to predict clinical outcomes based on severity. |
format | Online Article Text |
id | pubmed-7700532 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-77005322020-11-30 Modified Clavien–Dindo Classification and Outcome Prediction in Free Flap Reconstruction among Patients with Head and Neck Cancer Jan, Wei-Ling Chen, Hung-Chi Chang, Chang-Cheng Chen, Hsin-Han Shih, Pin-Keng Huang, Tsung-Chun J Clin Med Article Because of limitations caused by unique complications of free flap reconstruction, the Clavien–Dindo classification was modified to include grade “IIIc” for “partial or total free flap failure.” From 2013 to 2018, 116 patients who had undergone free flap reconstruction for head and neck cancer with grade III or higher postoperative complications were grouped using the “Modified” Clavien–Dindo classification. Alcoholism displayed significant predictive effects between grade IIIb and IIIc (72.7% vs. 50%, p = 0.028). Significant differences were observed between grade IIIb and IIIc in the duration of hospital stay (23.1 ± 10.1 vs. 28.6 ± 11.9 days, p = 0.015), duration of intensive care unit stay (6.0 ± 3.4 vs. 8.7 ± 4.3 days, p = 0.001), reoperation times during the current hospitalization (1.4 ± 0.8 vs. 2.0 ± 1.0 times, p < 0.001), and wound infection rate (29.9% vs. 62.5%, p = 0.002). The severity levels were significantly positively correlated with reoperation times during the current hospitalization (p < 0.001), ICU stay (p = 0.001), and hospital stay (p < 0.001). The modified Clavien–Dindo classification with grade IIIc describes the perioperative complications of head and neck free flap reconstruction to predict clinical outcomes based on severity. MDPI 2020-11-22 /pmc/articles/PMC7700532/ /pubmed/33266480 http://dx.doi.org/10.3390/jcm9113770 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Jan, Wei-Ling Chen, Hung-Chi Chang, Chang-Cheng Chen, Hsin-Han Shih, Pin-Keng Huang, Tsung-Chun Modified Clavien–Dindo Classification and Outcome Prediction in Free Flap Reconstruction among Patients with Head and Neck Cancer |
title | Modified Clavien–Dindo Classification and Outcome Prediction in Free Flap Reconstruction among Patients with Head and Neck Cancer |
title_full | Modified Clavien–Dindo Classification and Outcome Prediction in Free Flap Reconstruction among Patients with Head and Neck Cancer |
title_fullStr | Modified Clavien–Dindo Classification and Outcome Prediction in Free Flap Reconstruction among Patients with Head and Neck Cancer |
title_full_unstemmed | Modified Clavien–Dindo Classification and Outcome Prediction in Free Flap Reconstruction among Patients with Head and Neck Cancer |
title_short | Modified Clavien–Dindo Classification and Outcome Prediction in Free Flap Reconstruction among Patients with Head and Neck Cancer |
title_sort | modified clavien–dindo classification and outcome prediction in free flap reconstruction among patients with head and neck cancer |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700532/ https://www.ncbi.nlm.nih.gov/pubmed/33266480 http://dx.doi.org/10.3390/jcm9113770 |
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