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An Outbreak of Hepatitis A among Young Adult Men in Cyprus

Background: Outbreaks of acute hepatitis A (AHA) have recently been reported in Europe among men who have sex with men (MSM). The aim of this work was to evaluate, for the first time, trends in the reported cases of AHA in Cyprus over the last seven years. Methods: We retrospectively studied all peo...

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Autores principales: Dimitriou, Panagiotis, Nikolopoulos, Georgios K., Koliou, Maria, Constantinou, Elisavet, Azina, Chara, Panayiotou, Maria, Christaki, Eirini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700564/
https://www.ncbi.nlm.nih.gov/pubmed/33238551
http://dx.doi.org/10.3390/pathogens9110979
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author Dimitriou, Panagiotis
Nikolopoulos, Georgios K.
Koliou, Maria
Constantinou, Elisavet
Azina, Chara
Panayiotou, Maria
Christaki, Eirini
author_facet Dimitriou, Panagiotis
Nikolopoulos, Georgios K.
Koliou, Maria
Constantinou, Elisavet
Azina, Chara
Panayiotou, Maria
Christaki, Eirini
author_sort Dimitriou, Panagiotis
collection PubMed
description Background: Outbreaks of acute hepatitis A (AHA) have recently been reported in Europe among men who have sex with men (MSM). The aim of this work was to evaluate, for the first time, trends in the reported cases of AHA in Cyprus over the last seven years. Methods: We retrospectively studied all people reported with AHA in Cyprus between January 2013 and December 2019. Demographic data, type of transmission, vaccination status for HAV, laboratory and clinical data were analyzed. Results: The asnalysis involved 33 AHA cases (age 32.7 ± 17.4 years, 78.8% males). An increase in AHA reports was observed between July 2017 and June 2018 when more than a third (n = 13) of the cases of the period 2013–2019 were reported. The reporting rate of AHA doubled from 0.52 cases per 100,000 population (before July 2017) to 1.12 cases per 100,000 population (July 2017–June 2018). The male/female (M/F) ratio increased from one in 2013 to eight in 2018. Conclusion: An increase in AHA reports occurred in Cyprus between July 2017 and June 2018. Many cases with AHA in that period were MSM. Enhanced surveillance and timely public health interventions, like vaccination and awareness promotion, are important for preventing future outbreaks.
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spelling pubmed-77005642020-11-30 An Outbreak of Hepatitis A among Young Adult Men in Cyprus Dimitriou, Panagiotis Nikolopoulos, Georgios K. Koliou, Maria Constantinou, Elisavet Azina, Chara Panayiotou, Maria Christaki, Eirini Pathogens Article Background: Outbreaks of acute hepatitis A (AHA) have recently been reported in Europe among men who have sex with men (MSM). The aim of this work was to evaluate, for the first time, trends in the reported cases of AHA in Cyprus over the last seven years. Methods: We retrospectively studied all people reported with AHA in Cyprus between January 2013 and December 2019. Demographic data, type of transmission, vaccination status for HAV, laboratory and clinical data were analyzed. Results: The asnalysis involved 33 AHA cases (age 32.7 ± 17.4 years, 78.8% males). An increase in AHA reports was observed between July 2017 and June 2018 when more than a third (n = 13) of the cases of the period 2013–2019 were reported. The reporting rate of AHA doubled from 0.52 cases per 100,000 population (before July 2017) to 1.12 cases per 100,000 population (July 2017–June 2018). The male/female (M/F) ratio increased from one in 2013 to eight in 2018. Conclusion: An increase in AHA reports occurred in Cyprus between July 2017 and June 2018. Many cases with AHA in that period were MSM. Enhanced surveillance and timely public health interventions, like vaccination and awareness promotion, are important for preventing future outbreaks. MDPI 2020-11-23 /pmc/articles/PMC7700564/ /pubmed/33238551 http://dx.doi.org/10.3390/pathogens9110979 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dimitriou, Panagiotis
Nikolopoulos, Georgios K.
Koliou, Maria
Constantinou, Elisavet
Azina, Chara
Panayiotou, Maria
Christaki, Eirini
An Outbreak of Hepatitis A among Young Adult Men in Cyprus
title An Outbreak of Hepatitis A among Young Adult Men in Cyprus
title_full An Outbreak of Hepatitis A among Young Adult Men in Cyprus
title_fullStr An Outbreak of Hepatitis A among Young Adult Men in Cyprus
title_full_unstemmed An Outbreak of Hepatitis A among Young Adult Men in Cyprus
title_short An Outbreak of Hepatitis A among Young Adult Men in Cyprus
title_sort outbreak of hepatitis a among young adult men in cyprus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700564/
https://www.ncbi.nlm.nih.gov/pubmed/33238551
http://dx.doi.org/10.3390/pathogens9110979
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