A Case of Vanishing Bile Duct Syndrome after Drug-Induced Liver Injury Caused by Pelubiprofen

Vanishing bile duct syndrome (VBDS) is a rare disease characterized by ductopenia and cholestasis, and is linked to immunological damage to the bile duct system. VBDS can be triggered by infection, ischemia, autoimmune diseases, adverse drug reactions, and humoral factors associated with malignancy....

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Autores principales: Bak, Haein, Kim, Hayeon, Lee, Sieun, Lee, Yoonseok, Bang, Soo-Min, Lee, Young-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700876/
https://www.ncbi.nlm.nih.gov/pubmed/33251781
http://dx.doi.org/10.3349/ymj.2020.61.12.1060
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author Bak, Haein
Kim, Hayeon
Lee, Sieun
Lee, Yoonseok
Bang, Soo-Min
Lee, Young-Sun
author_facet Bak, Haein
Kim, Hayeon
Lee, Sieun
Lee, Yoonseok
Bang, Soo-Min
Lee, Young-Sun
author_sort Bak, Haein
collection PubMed
description Vanishing bile duct syndrome (VBDS) is a rare disease characterized by ductopenia and cholestasis, and is linked to immunological damage to the bile duct system. VBDS can be triggered by infection, ischemia, autoimmune diseases, adverse drug reactions, and humoral factors associated with malignancy. A few cases of VBDS associated with nonsteroidal anti-inflammatory drug-related drug-induced liver injury (DILI) have been reported. Here, we report a case of a 29-year-old patient who developed DILI that progressed to VBDS after the administration of pelubiprofen.
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spelling pubmed-77008762020-12-06 A Case of Vanishing Bile Duct Syndrome after Drug-Induced Liver Injury Caused by Pelubiprofen Bak, Haein Kim, Hayeon Lee, Sieun Lee, Yoonseok Bang, Soo-Min Lee, Young-Sun Yonsei Med J Case Report Vanishing bile duct syndrome (VBDS) is a rare disease characterized by ductopenia and cholestasis, and is linked to immunological damage to the bile duct system. VBDS can be triggered by infection, ischemia, autoimmune diseases, adverse drug reactions, and humoral factors associated with malignancy. A few cases of VBDS associated with nonsteroidal anti-inflammatory drug-related drug-induced liver injury (DILI) have been reported. Here, we report a case of a 29-year-old patient who developed DILI that progressed to VBDS after the administration of pelubiprofen. Yonsei University College of Medicine 2020-12-01 2020-11-25 /pmc/articles/PMC7700876/ /pubmed/33251781 http://dx.doi.org/10.3349/ymj.2020.61.12.1060 Text en © Copyright: Yonsei University College of Medicine 2020 https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bak, Haein
Kim, Hayeon
Lee, Sieun
Lee, Yoonseok
Bang, Soo-Min
Lee, Young-Sun
A Case of Vanishing Bile Duct Syndrome after Drug-Induced Liver Injury Caused by Pelubiprofen
title A Case of Vanishing Bile Duct Syndrome after Drug-Induced Liver Injury Caused by Pelubiprofen
title_full A Case of Vanishing Bile Duct Syndrome after Drug-Induced Liver Injury Caused by Pelubiprofen
title_fullStr A Case of Vanishing Bile Duct Syndrome after Drug-Induced Liver Injury Caused by Pelubiprofen
title_full_unstemmed A Case of Vanishing Bile Duct Syndrome after Drug-Induced Liver Injury Caused by Pelubiprofen
title_short A Case of Vanishing Bile Duct Syndrome after Drug-Induced Liver Injury Caused by Pelubiprofen
title_sort case of vanishing bile duct syndrome after drug-induced liver injury caused by pelubiprofen
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700876/
https://www.ncbi.nlm.nih.gov/pubmed/33251781
http://dx.doi.org/10.3349/ymj.2020.61.12.1060
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