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Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans
PURPOSE: Maximum leaf speed is a configurable parameter of MLC in a treatment‐planning system. This study investigated the influence of MLC on the quality of VMAT plans. METHODS: Seven MLCs with different maximum leaf speeds (1.0, 1.5, 2.25, 3.5, 5.0, 7.5, and 10 cm/s) were configured for an acceler...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700941/ https://www.ncbi.nlm.nih.gov/pubmed/33047486 http://dx.doi.org/10.1002/acm2.13020 |
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author | Chen, Jiayun Cui, Weijie Fu, Qi Zhang, Haojia Huang, Xiaodong Han, Fei Xia, Wenlong Liang, Bin Dai, Jianrong |
author_facet | Chen, Jiayun Cui, Weijie Fu, Qi Zhang, Haojia Huang, Xiaodong Han, Fei Xia, Wenlong Liang, Bin Dai, Jianrong |
author_sort | Chen, Jiayun |
collection | PubMed |
description | PURPOSE: Maximum leaf speed is a configurable parameter of MLC in a treatment‐planning system. This study investigated the influence of MLC on the quality of VMAT plans. METHODS: Seven MLCs with different maximum leaf speeds (1.0, 1.5, 2.25, 3.5, 5.0, 7.5, and 10 cm/s) were configured for an accelerator in treatment‐planning system. Correspondingly, seven treatment plans, with the identical initial optimization parameter, were designed with the mdaccAutoPlan system. Six nasopharyngeal carcinoma (NPC) patients and nine rectal cancer patients were selected, representing complex and simple clinical circumstances. VMAT plan quality was evaluated with PlanIQ(TM) software. The results were statistically analyzed with a one‐way analysis of variance (ANOVA) and pairwise comparison tests. RESULTS: The relative changes of plan scores achieved by the seven configured accelerators, with specific maximum MLC leaf speed (MMLS) for each patient, were studied. Two apparent trends of MMLS influence on VMAT plan scores were observed: Plan scores increased with MMLS; Plan scores increased rapidly when MMLS increased from 1 to 3.5, thus the relative change of plan score decreased in this MMLS range. The stationary point of maximum MLC speed (MMSSP) is defined, for the specific MMLS when the relative changes of plan scores is first <5%, as MMLS increases from 1.0 to 10. For rectal plans, MMSSPs were 2.25 for six patients and 3.5 for the other three patients. For NPC plans, MMSSPs were 3.5 for five patients and 2.25 for one patient. CONCLUSION: This work indicates that MMLS directly influences VMAT plan quality in NPC cases and rectal cancer cases. VMAT plan quality improved conspicuously as MMLS increased from 1 to 3.5, VMAT plan quality with marginal improvement when MMLS is above 3.5. |
format | Online Article Text |
id | pubmed-7700941 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77009412020-12-03 Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans Chen, Jiayun Cui, Weijie Fu, Qi Zhang, Haojia Huang, Xiaodong Han, Fei Xia, Wenlong Liang, Bin Dai, Jianrong J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: Maximum leaf speed is a configurable parameter of MLC in a treatment‐planning system. This study investigated the influence of MLC on the quality of VMAT plans. METHODS: Seven MLCs with different maximum leaf speeds (1.0, 1.5, 2.25, 3.5, 5.0, 7.5, and 10 cm/s) were configured for an accelerator in treatment‐planning system. Correspondingly, seven treatment plans, with the identical initial optimization parameter, were designed with the mdaccAutoPlan system. Six nasopharyngeal carcinoma (NPC) patients and nine rectal cancer patients were selected, representing complex and simple clinical circumstances. VMAT plan quality was evaluated with PlanIQ(TM) software. The results were statistically analyzed with a one‐way analysis of variance (ANOVA) and pairwise comparison tests. RESULTS: The relative changes of plan scores achieved by the seven configured accelerators, with specific maximum MLC leaf speed (MMLS) for each patient, were studied. Two apparent trends of MMLS influence on VMAT plan scores were observed: Plan scores increased with MMLS; Plan scores increased rapidly when MMLS increased from 1 to 3.5, thus the relative change of plan score decreased in this MMLS range. The stationary point of maximum MLC speed (MMSSP) is defined, for the specific MMLS when the relative changes of plan scores is first <5%, as MMLS increases from 1.0 to 10. For rectal plans, MMSSPs were 2.25 for six patients and 3.5 for the other three patients. For NPC plans, MMSSPs were 3.5 for five patients and 2.25 for one patient. CONCLUSION: This work indicates that MMLS directly influences VMAT plan quality in NPC cases and rectal cancer cases. VMAT plan quality improved conspicuously as MMLS increased from 1 to 3.5, VMAT plan quality with marginal improvement when MMLS is above 3.5. John Wiley and Sons Inc. 2020-10-12 /pmc/articles/PMC7700941/ /pubmed/33047486 http://dx.doi.org/10.1002/acm2.13020 Text en © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Chen, Jiayun Cui, Weijie Fu, Qi Zhang, Haojia Huang, Xiaodong Han, Fei Xia, Wenlong Liang, Bin Dai, Jianrong Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans |
title | Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans |
title_full | Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans |
title_fullStr | Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans |
title_full_unstemmed | Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans |
title_short | Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans |
title_sort | influence of maximum mlc leaf speed on the quality of volumetric modulated arc therapy plans |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700941/ https://www.ncbi.nlm.nih.gov/pubmed/33047486 http://dx.doi.org/10.1002/acm2.13020 |
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