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Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans

PURPOSE: Maximum leaf speed is a configurable parameter of MLC in a treatment‐planning system. This study investigated the influence of MLC on the quality of VMAT plans. METHODS: Seven MLCs with different maximum leaf speeds (1.0, 1.5, 2.25, 3.5, 5.0, 7.5, and 10 cm/s) were configured for an acceler...

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Detalles Bibliográficos
Autores principales: Chen, Jiayun, Cui, Weijie, Fu, Qi, Zhang, Haojia, Huang, Xiaodong, Han, Fei, Xia, Wenlong, Liang, Bin, Dai, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700941/
https://www.ncbi.nlm.nih.gov/pubmed/33047486
http://dx.doi.org/10.1002/acm2.13020
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author Chen, Jiayun
Cui, Weijie
Fu, Qi
Zhang, Haojia
Huang, Xiaodong
Han, Fei
Xia, Wenlong
Liang, Bin
Dai, Jianrong
author_facet Chen, Jiayun
Cui, Weijie
Fu, Qi
Zhang, Haojia
Huang, Xiaodong
Han, Fei
Xia, Wenlong
Liang, Bin
Dai, Jianrong
author_sort Chen, Jiayun
collection PubMed
description PURPOSE: Maximum leaf speed is a configurable parameter of MLC in a treatment‐planning system. This study investigated the influence of MLC on the quality of VMAT plans. METHODS: Seven MLCs with different maximum leaf speeds (1.0, 1.5, 2.25, 3.5, 5.0, 7.5, and 10 cm/s) were configured for an accelerator in treatment‐planning system. Correspondingly, seven treatment plans, with the identical initial optimization parameter, were designed with the mdaccAutoPlan system. Six nasopharyngeal carcinoma (NPC) patients and nine rectal cancer patients were selected, representing complex and simple clinical circumstances. VMAT plan quality was evaluated with PlanIQ(TM) software. The results were statistically analyzed with a one‐way analysis of variance (ANOVA) and pairwise comparison tests. RESULTS: The relative changes of plan scores achieved by the seven configured accelerators, with specific maximum MLC leaf speed (MMLS) for each patient, were studied. Two apparent trends of MMLS influence on VMAT plan scores were observed: Plan scores increased with MMLS; Plan scores increased rapidly when MMLS increased from 1 to 3.5, thus the relative change of plan score decreased in this MMLS range. The stationary point of maximum MLC speed (MMSSP) is defined, for the specific MMLS when the relative changes of plan scores is first <5%, as MMLS increases from 1.0 to 10. For rectal plans, MMSSPs were 2.25 for six patients and 3.5 for the other three patients. For NPC plans, MMSSPs were 3.5 for five patients and 2.25 for one patient. CONCLUSION: This work indicates that MMLS directly influences VMAT plan quality in NPC cases and rectal cancer cases. VMAT plan quality improved conspicuously as MMLS increased from 1 to 3.5, VMAT plan quality with marginal improvement when MMLS is above 3.5.
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spelling pubmed-77009412020-12-03 Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans Chen, Jiayun Cui, Weijie Fu, Qi Zhang, Haojia Huang, Xiaodong Han, Fei Xia, Wenlong Liang, Bin Dai, Jianrong J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: Maximum leaf speed is a configurable parameter of MLC in a treatment‐planning system. This study investigated the influence of MLC on the quality of VMAT plans. METHODS: Seven MLCs with different maximum leaf speeds (1.0, 1.5, 2.25, 3.5, 5.0, 7.5, and 10 cm/s) were configured for an accelerator in treatment‐planning system. Correspondingly, seven treatment plans, with the identical initial optimization parameter, were designed with the mdaccAutoPlan system. Six nasopharyngeal carcinoma (NPC) patients and nine rectal cancer patients were selected, representing complex and simple clinical circumstances. VMAT plan quality was evaluated with PlanIQ(TM) software. The results were statistically analyzed with a one‐way analysis of variance (ANOVA) and pairwise comparison tests. RESULTS: The relative changes of plan scores achieved by the seven configured accelerators, with specific maximum MLC leaf speed (MMLS) for each patient, were studied. Two apparent trends of MMLS influence on VMAT plan scores were observed: Plan scores increased with MMLS; Plan scores increased rapidly when MMLS increased from 1 to 3.5, thus the relative change of plan score decreased in this MMLS range. The stationary point of maximum MLC speed (MMSSP) is defined, for the specific MMLS when the relative changes of plan scores is first <5%, as MMLS increases from 1.0 to 10. For rectal plans, MMSSPs were 2.25 for six patients and 3.5 for the other three patients. For NPC plans, MMSSPs were 3.5 for five patients and 2.25 for one patient. CONCLUSION: This work indicates that MMLS directly influences VMAT plan quality in NPC cases and rectal cancer cases. VMAT plan quality improved conspicuously as MMLS increased from 1 to 3.5, VMAT plan quality with marginal improvement when MMLS is above 3.5. John Wiley and Sons Inc. 2020-10-12 /pmc/articles/PMC7700941/ /pubmed/33047486 http://dx.doi.org/10.1002/acm2.13020 Text en © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Chen, Jiayun
Cui, Weijie
Fu, Qi
Zhang, Haojia
Huang, Xiaodong
Han, Fei
Xia, Wenlong
Liang, Bin
Dai, Jianrong
Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans
title Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans
title_full Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans
title_fullStr Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans
title_full_unstemmed Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans
title_short Influence of maximum MLC leaf speed on the quality of volumetric modulated arc therapy plans
title_sort influence of maximum mlc leaf speed on the quality of volumetric modulated arc therapy plans
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700941/
https://www.ncbi.nlm.nih.gov/pubmed/33047486
http://dx.doi.org/10.1002/acm2.13020
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