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A case report of prostate cancer presenting as a symptomatic pelvic mass mimicking lymphoma

INTRODUCTION: Metastatic prostate cancer is a relatively common condition in elderly men. The aim of this paper is to report a rare case of metastatic prostate cancer presenting as a large pelvic mass mimicking lymphoma and to discuss its management. PRESENTATION OF CASE: An 85-year-old patient was...

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Autores principales: Mahjoubi, Zied, Bibi, Mokhtar, Hedhli, Houssem, Ouanes, Yassine, Rhouma, Sami Ben, Yassine, Nouira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700973/
https://www.ncbi.nlm.nih.gov/pubmed/33395830
http://dx.doi.org/10.1016/j.ijscr.2020.11.042
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author Mahjoubi, Zied
Bibi, Mokhtar
Hedhli, Houssem
Ouanes, Yassine
Rhouma, Sami Ben
Yassine, Nouira
author_facet Mahjoubi, Zied
Bibi, Mokhtar
Hedhli, Houssem
Ouanes, Yassine
Rhouma, Sami Ben
Yassine, Nouira
author_sort Mahjoubi, Zied
collection PubMed
description INTRODUCTION: Metastatic prostate cancer is a relatively common condition in elderly men. The aim of this paper is to report a rare case of metastatic prostate cancer presenting as a large pelvic mass mimicking lymphoma and to discuss its management. PRESENTATION OF CASE: An 85-year-old patient was complaining of lower urinary tract symptoms, and significant pelvic swelling. On physical examination, a 15-cm pelvic mass and lumpy prostate were found. Laboratory investigations revealed elevated PSA levels (PSA=300g/mL). CT scan showed a large lobulated necrotic pelvic mass and multiple swollen lymphnodes. The diagnosis of an atypical pelvic lymphoma associated with a metastatic prostate cancer was first evoked. An ultrasonography-guided biopsy of the mass was carried. The immunohistochemical study confirmed prostate adenocarcinoma. A bilateral orchiectomy was performed. A follow up of 3 months showed a decrease of PSA without shrinkage of the mass. DISCUSSION: A metastatic prostate cancer presenting as a compressive pelvic mass mimicking other diagnosis such as lymphomas, is a rare circumstance of discovery. In our case, atypical pelvic lymphoma was evoked based on the association of multiple retroperitoneal enlarged lymphnodes. Histological findings of the biopsy rectified the diagnosis and confirmed prostate adenocarcinoma. The main treatment for such metastatic prostate cancers remains hormone therapy. Some authors reported external beam radiotherapy in order to reduce prostate volume. CONCLUSION: Prostate cancer should be considered in the assessment of large pelvic masses. Digital rectal examination and testing PSA levels can lead to the diagnosis. After histological confirmation, the androgen deprivation is the main treatment.
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spelling pubmed-77009732020-12-07 A case report of prostate cancer presenting as a symptomatic pelvic mass mimicking lymphoma Mahjoubi, Zied Bibi, Mokhtar Hedhli, Houssem Ouanes, Yassine Rhouma, Sami Ben Yassine, Nouira Int J Surg Case Rep Case Report INTRODUCTION: Metastatic prostate cancer is a relatively common condition in elderly men. The aim of this paper is to report a rare case of metastatic prostate cancer presenting as a large pelvic mass mimicking lymphoma and to discuss its management. PRESENTATION OF CASE: An 85-year-old patient was complaining of lower urinary tract symptoms, and significant pelvic swelling. On physical examination, a 15-cm pelvic mass and lumpy prostate were found. Laboratory investigations revealed elevated PSA levels (PSA=300g/mL). CT scan showed a large lobulated necrotic pelvic mass and multiple swollen lymphnodes. The diagnosis of an atypical pelvic lymphoma associated with a metastatic prostate cancer was first evoked. An ultrasonography-guided biopsy of the mass was carried. The immunohistochemical study confirmed prostate adenocarcinoma. A bilateral orchiectomy was performed. A follow up of 3 months showed a decrease of PSA without shrinkage of the mass. DISCUSSION: A metastatic prostate cancer presenting as a compressive pelvic mass mimicking other diagnosis such as lymphomas, is a rare circumstance of discovery. In our case, atypical pelvic lymphoma was evoked based on the association of multiple retroperitoneal enlarged lymphnodes. Histological findings of the biopsy rectified the diagnosis and confirmed prostate adenocarcinoma. The main treatment for such metastatic prostate cancers remains hormone therapy. Some authors reported external beam radiotherapy in order to reduce prostate volume. CONCLUSION: Prostate cancer should be considered in the assessment of large pelvic masses. Digital rectal examination and testing PSA levels can lead to the diagnosis. After histological confirmation, the androgen deprivation is the main treatment. Elsevier 2020-11-11 /pmc/articles/PMC7700973/ /pubmed/33395830 http://dx.doi.org/10.1016/j.ijscr.2020.11.042 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Mahjoubi, Zied
Bibi, Mokhtar
Hedhli, Houssem
Ouanes, Yassine
Rhouma, Sami Ben
Yassine, Nouira
A case report of prostate cancer presenting as a symptomatic pelvic mass mimicking lymphoma
title A case report of prostate cancer presenting as a symptomatic pelvic mass mimicking lymphoma
title_full A case report of prostate cancer presenting as a symptomatic pelvic mass mimicking lymphoma
title_fullStr A case report of prostate cancer presenting as a symptomatic pelvic mass mimicking lymphoma
title_full_unstemmed A case report of prostate cancer presenting as a symptomatic pelvic mass mimicking lymphoma
title_short A case report of prostate cancer presenting as a symptomatic pelvic mass mimicking lymphoma
title_sort case report of prostate cancer presenting as a symptomatic pelvic mass mimicking lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700973/
https://www.ncbi.nlm.nih.gov/pubmed/33395830
http://dx.doi.org/10.1016/j.ijscr.2020.11.042
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