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Data Mining for Adverse Events of Tumor Necrosis Factor-Alpha Inhibitors in Pediatric Patients: Tree-Based Scan Statistic Analyses of Danish Nationwide Health Data
BACKGROUND AND OBJECTIVES: Tumor necrosis factor-alpha (TNF-α) inhibitors are efficacious and considered generally safe in adults. However, pediatric-specific safety evidence is scarce. The aim of this study was to screen for signals of previously unknown adverse events of TNF-α inhibitors in pediat...
Autores principales: | Wintzell, Viktor, Svanström, Henrik, Melbye, Mads, Ludvigsson, Jonas F., Pasternak, Björn, Kulldorff, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701063/ https://www.ncbi.nlm.nih.gov/pubmed/33104987 http://dx.doi.org/10.1007/s40261-020-00977-5 |
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