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Fabrication of a pediatric torso phantom with multiple tissues represented using a dual nozzle thermoplastic 3D printer
PURPOSE: To demonstrate an on‐demand and nearly automatic method for fabricating tissue‐equivalent physical anthropomorphic phantoms for imaging and dosimetry applications using a dual nozzle thermoplastic three‐dimensional (3D) printer and two types of plastic. METHODS: Two 3D printing plastics wer...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701110/ https://www.ncbi.nlm.nih.gov/pubmed/33073922 http://dx.doi.org/10.1002/acm2.13064 |
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author | Mille, Matthew M. Griffin, Keith T. Maass‐Moreno, Roberto Lee, Choonsik |
author_facet | Mille, Matthew M. Griffin, Keith T. Maass‐Moreno, Roberto Lee, Choonsik |
author_sort | Mille, Matthew M. |
collection | PubMed |
description | PURPOSE: To demonstrate an on‐demand and nearly automatic method for fabricating tissue‐equivalent physical anthropomorphic phantoms for imaging and dosimetry applications using a dual nozzle thermoplastic three‐dimensional (3D) printer and two types of plastic. METHODS: Two 3D printing plastics were investigated: (a) Normal polylactic acid (PLA) as a soft tissue simulant and (b) Iron PLA (PLA‐Fe), a composite of PLA and iron powder, as a bone simulant. The plastics and geometry of a 1‐yr‐old computational phantom were combined with a dual extrusion 3D printer to fabricate an anthropomorphic imaging phantom. The volumetric fill density of the 3D‐printed parts was varied to approximate tissues of different radiographic density using a calibration curve relating the printer infill density setting to measured CT number. As a demonstration of our method we printed a 10 cm axial cross‐section of the computational phantom’s torso at full scale. We imaged the phantom on a CT scanner and compared HU values to those of a 1‐yr‐old patient and a commercial 5‐yr‐old physical phantom. RESULTS: The phantom was printed in six parts over the course of a week. The printed phantom included 30 separate anatomical regions including soft tissue remainder, lungs (left and right), heart, esophagus, rib cage (left and right ribs 1 to 10), clavicles (left and right), scapulae (left and right), thoracic vertebrae (one solid object defining thoracic vertebrae T1 to T9). CT scanning of the phantom showed five distinct radiographic regions (heart, lung, soft tissue remainder, bone, and air cavity) despite using only two types of plastic. The 3D‐printed phantom demonstrated excellent similarity to commercially available phantoms, although key limitations in the printer and printing materials leave opportunity for improvement. CONCLUSION: Patient‐specific anthropomorphic phantoms can be 3D printed and assembled in sections for imaging and dosimetry applications. Such phantoms will be useful for dose verification purposes when commercial phantoms are unavailable for purchase in the specific anatomies of interest. |
format | Online Article Text |
id | pubmed-7701110 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77011102020-12-03 Fabrication of a pediatric torso phantom with multiple tissues represented using a dual nozzle thermoplastic 3D printer Mille, Matthew M. Griffin, Keith T. Maass‐Moreno, Roberto Lee, Choonsik J Appl Clin Med Phys Medical Imaging PURPOSE: To demonstrate an on‐demand and nearly automatic method for fabricating tissue‐equivalent physical anthropomorphic phantoms for imaging and dosimetry applications using a dual nozzle thermoplastic three‐dimensional (3D) printer and two types of plastic. METHODS: Two 3D printing plastics were investigated: (a) Normal polylactic acid (PLA) as a soft tissue simulant and (b) Iron PLA (PLA‐Fe), a composite of PLA and iron powder, as a bone simulant. The plastics and geometry of a 1‐yr‐old computational phantom were combined with a dual extrusion 3D printer to fabricate an anthropomorphic imaging phantom. The volumetric fill density of the 3D‐printed parts was varied to approximate tissues of different radiographic density using a calibration curve relating the printer infill density setting to measured CT number. As a demonstration of our method we printed a 10 cm axial cross‐section of the computational phantom’s torso at full scale. We imaged the phantom on a CT scanner and compared HU values to those of a 1‐yr‐old patient and a commercial 5‐yr‐old physical phantom. RESULTS: The phantom was printed in six parts over the course of a week. The printed phantom included 30 separate anatomical regions including soft tissue remainder, lungs (left and right), heart, esophagus, rib cage (left and right ribs 1 to 10), clavicles (left and right), scapulae (left and right), thoracic vertebrae (one solid object defining thoracic vertebrae T1 to T9). CT scanning of the phantom showed five distinct radiographic regions (heart, lung, soft tissue remainder, bone, and air cavity) despite using only two types of plastic. The 3D‐printed phantom demonstrated excellent similarity to commercially available phantoms, although key limitations in the printer and printing materials leave opportunity for improvement. CONCLUSION: Patient‐specific anthropomorphic phantoms can be 3D printed and assembled in sections for imaging and dosimetry applications. Such phantoms will be useful for dose verification purposes when commercial phantoms are unavailable for purchase in the specific anatomies of interest. John Wiley and Sons Inc. 2020-10-19 /pmc/articles/PMC7701110/ /pubmed/33073922 http://dx.doi.org/10.1002/acm2.13064 Text en © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Medical Imaging Mille, Matthew M. Griffin, Keith T. Maass‐Moreno, Roberto Lee, Choonsik Fabrication of a pediatric torso phantom with multiple tissues represented using a dual nozzle thermoplastic 3D printer |
title | Fabrication of a pediatric torso phantom with multiple tissues represented using a dual nozzle thermoplastic 3D printer |
title_full | Fabrication of a pediatric torso phantom with multiple tissues represented using a dual nozzle thermoplastic 3D printer |
title_fullStr | Fabrication of a pediatric torso phantom with multiple tissues represented using a dual nozzle thermoplastic 3D printer |
title_full_unstemmed | Fabrication of a pediatric torso phantom with multiple tissues represented using a dual nozzle thermoplastic 3D printer |
title_short | Fabrication of a pediatric torso phantom with multiple tissues represented using a dual nozzle thermoplastic 3D printer |
title_sort | fabrication of a pediatric torso phantom with multiple tissues represented using a dual nozzle thermoplastic 3d printer |
topic | Medical Imaging |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701110/ https://www.ncbi.nlm.nih.gov/pubmed/33073922 http://dx.doi.org/10.1002/acm2.13064 |
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