Cargando…

Interleukin-17A Facilitates Chikungunya Virus Infection by Inhibiting IFN-α2 Expression

Interferons (IFNs) are the key components of innate immunity and are crucial for host defense against viral infections. Here, we report a novel role of interleukin-17A (IL-17A) in inhibiting IFN-α2 expression thus promoting chikungunya virus (CHIKV) infection. CHIKV infected IL-17A deficient (Il17a(...

Descripción completa

Detalles Bibliográficos
Autores principales:	Neupane, Biswas, Acharya, Dhiraj, Nazneen, Farzana, Gonzalez-Fernandez, Gabriel, Flynt, Alex Sutton, Bai, Fengwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701120/ https://www.ncbi.nlm.nih.gov/pubmed/33304351 http://dx.doi.org/10.3389/fimmu.2020.588382

Ejemplares similares

Murine Trophoblast Stem Cells and Their Differentiated Cells Attenuate Zika Virus In Vitro by Reducing Glycosylation of the Viral Envelope Protein
por: Neupane, Biswas, et al.
Publicado: (2021)

Loss of Glycosaminoglycan Receptor Binding after Mosquito Cell Passage Reduces Chikungunya Virus Infectivity
por: Acharya, Dhiraj, et al.
Publicado: (2015)

The Roles of Osteopontin in the Pathogenesis of West Nile Encephalitis
por: Nazneen, Farzana, et al.
Publicado: (2020)

Inhibition of Myeloid Differentiation Factor 88 Reduces Human and Mouse T-Cell Interleukin-17 and IFNγ Production and Ameliorates Experimental Autoimmune Encephalomyelitis Induced in Mice
por: Dishon, Shira, et al.
Publicado: (2017)

Interleukin-17 Contributes to Chikungunya Virus-Induced Disease
por: Liu, Xiang, et al.
Publicado: (2022)

In vitro and in vivo efficacy of anti‐chikungunya virus monoclonal antibodies produced in wild‐type and glycoengineered Nicotiana benthamiana plants
por: Hurtado, Jonathan, et al.
Publicado: (2019)

Context Is Key: Delineating the Unique Functions of IFNα and IFNβ in Disease
por: Fox, Lindsey E., et al.
Publicado: (2020)

IFNα Inducible Models of Murine SLE
por: Liu, Zheng, et al.
Publicado: (2013)

Constitutive IFNα Protein Production in Bats
por: Bondet, Vincent, et al.
Publicado: (2021)

Role of Interleukin-17 in Acute Pancreatitis
por: Li, Guanqun, et al.
Publicado: (2021)

Salivary interleukin 6, interleukin 8, interleukin 17A, and tumour necrosis factor α levels in patients with periodontitis and rheumatoid arthritis
por: Kaczyński, Tomasz, et al.
Publicado: (2019)

The Interleukin-23/Interleukin-17 Axis Links Adaptive and Innate Immunity in Psoriasis
por: Schön, Michael P., et al.
Publicado: (2018)

Interleukin-17 in Chronic Inflammatory Neurological Diseases
por: Milovanovic, Jelena, et al.
Publicado: (2020)

An Overview of Current Approaches Toward the Treatment and Prevention of West Nile Virus Infection
por: Acharya, Dhiraj, et al.
Publicado: (2016)

Congenital Zika Virus Infection in Immunocompetent Mice Causes Postnatal Growth Impediment and Neurobehavioral Deficits
por: Paul, Amber M., et al.
Publicado: (2018)

Biology of Interleukin-17 and Its Pathophysiological Significance in Sepsis
por: Ge, Yun, et al.
Publicado: (2020)

Interleukin-17A Interweaves the Skeletal and Immune Systems
por: Tang, Mengjia, et al.
Publicado: (2021)

Contribution of Interleukin-17A to Retinal Degenerative Diseases
por: Zhong, Huimin, et al.
Publicado: (2022)

IFNα subtype-specific susceptibility of HBV in the course of chronic infection
por: Xie, Xiaohong, et al.
Publicado: (2022)

Interleukin-1-Interleukin-17 Signaling Axis Induces Cartilage Destruction and Promotes Experimental Osteoarthritis
por: Na, Hyun Sik, et al.
Publicado: (2020)

Targeting the Interleukin-23/Interleukin-17 Inflammatory Pathway: Successes and Failures in the Treatment of Axial Spondyloarthritis
por: Wang, Runsheng, et al.
Publicado: (2021)

IFN-α induced systemic lupus erythematosus complicated with hemophagocytic lymphohistiocytosis: a case report and literature review
por: Zeng, Zhipeng, et al.
Publicado: (2023)

Treatment With Cladribine Selects IFNγ+IL17+ T Cells in RRMS Patients – An In Vitro Study
por: Dobreanu, Minodora, et al.
Publicado: (2021)

Adenovirus vectored IFN-α protects mice from lethal challenge of Chikungunya virus infection
por: Chen, Huixin, et al.
Publicado: (2020)

Corrigendum: Interleukin-1-Interleukin-17 Signaling Axis Induces Cartilage Destruction and Promotes Experimental Osteoarthritis
por: Na, Hyun Sik, et al.
Publicado: (2020)

Interleukin-22 Influences the Th1/Th17 Axis
por: Lindahl, Hannes, et al.
Publicado: (2021)

Interleukin-17 as a potential therapeutic target for chronic pain
por: Jiang, Xiaojuan, et al.
Publicado: (2022)

Diverse Anti-Tumor Immune Potential Driven by Individual IFNα Subtypes
por: Buzzai, Anthony C., et al.
Publicado: (2020)

From IL-17 to IFN-γ in inflammatory skin disorders: Is transdifferentiation a potential treatment target?
por: Belpaire, Arno, et al.
Publicado: (2022)

Imidazoquinolines with improved pharmacokinetic properties induce a high IFNα to TNFα ratio in vitro and in vivo
por: Keppler, Manuel, et al.
Publicado: (2023)

Increased TNF-α/IFN-γ/IL-2 and Decreased TNF-α/IFN-γ Production by Central Memory T Cells Are Associated with Protective Responses against Bovine Tuberculosis Following BCG Vaccination
por: Maggioli, Mayara F., et al.
Publicado: (2016)

An effective live-attenuated Zika vaccine candidate with a modified 5′ untranslated region
por: Nazneen, Farzana, et al.
Publicado: (2023)

Predominance of interleukin-22 over interleukin-17 at the site of disease in human tuberculosis
por: Matthews, Kerryn, et al.
Publicado: (2011)

Release of Interleukin-1α or Interleukin-1β Depends on Mechanism of Cell Death
por: England, Hazel, et al.
Publicado: (2014)

Cerebral and ocular toxoplasmosis related with IFN-γ, TNF-α, and IL-10 levels
por: Meira, Cristina S., et al.
Publicado: (2014)

Regulatory T-Cells Mediate IFN-α-Induced Resistance against Antigen-Induced Arthritis
por: Chenna Narendra, Sudeep, et al.
Publicado: (2018)

Tetracyclines Diminish In Vitro IFN-γ and IL-17-Producing Adaptive and Innate Immune Cells in Multiple Sclerosis
por: Florou, Despoina T., et al.
Publicado: (2021)

Interleukin-25 Produced by Synoviocytes Has Anti-inflammatory Effects by Acting As a Receptor Antagonist for Interleukin-17A Function
por: Lavocat, Fabien, et al.
Publicado: (2017)

ISR8/IRF1-AS1 Is Relevant for IFNα and NF-κB Responses
por: Barriocanal, Marina, et al.
Publicado: (2022)

Microglia shield the murine brain from damage mediated by the cytokines IL-6 and IFN-α
por: West, Phillip K., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vccfda19hu7sl5linqcqlvmc0t