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Adjuvanted Schistosoma mansoni-Cathepsin B With Sulfated Lactosyl Archaeol Archaeosomes or AddaVax™ Provides Protection in a Pre-Clinical Schistosomiasis Model
Schistosomiasis threatens 800 million people worldwide. Chronic pathology manifests as hepatosplenomegaly, and intestinal schistosomiasis caused by Schistosoma mansoni can lead to liver fibrosis, cirrhosis, and blood in the stool. To assist the only FDA-approved drug, praziquantel, in parasite elimi...
Autores principales: | Perera, Dilhan J., Hassan, Adam S., Jia, Yimei, Ricciardi, Alessandra, McCluskie, Michael J., Weeratna, Risini D., Ndao, Momar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701121/ https://www.ncbi.nlm.nih.gov/pubmed/33304354 http://dx.doi.org/10.3389/fimmu.2020.605288 |
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