Repurposing Known Drugs as Covalent and Non-covalent Inhibitors of the SARS-CoV-2 Papain-Like Protease

In the absence of an approved vaccine, developing effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals is essential to tackle the current pandemic health crisis due to the coronavirus disease 2019 (COVID-19) spread. As any traditional drug discovery program is a time-con...

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Detalles Bibliográficos
Autores principales: Delre, Pietro, Caporuscio, Fabiana, Saviano, Michele, Mangiatordi, Giuseppe Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701290/
https://www.ncbi.nlm.nih.gov/pubmed/33304884
http://dx.doi.org/10.3389/fchem.2020.594009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701290/
https://www.ncbi.nlm.nih.gov/pubmed/33304884
http://dx.doi.org/10.3389/fchem.2020.594009

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