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A Non-severe Coronavirus Disease 2019 Patient With Persistently High Interleukin-6 Level

Interleukin 6 (IL-6) is one of the markers of immune system activation indicating existent infection and inflammation. We present here a case of a 55-year-old male COVID-19 patient with an unusual high level of interleukin 6 (IL-6). Further investigation revealed he had hepatocellular carcinoma (HCC...

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Detalles Bibliográficos
Autores principales: Hambali, Nurfarah Lydia, Mohd Noh, Malehah, Paramasivam, Shahleni, Chua, Tock Hing, Hayati, Firdaus, Payus, Alvin Oliver, Tee, Tze Yuan, Rosli, Khairul Taufiq, Abd Rachman Isnadi, Mohammad Faruq, Manin, Benny O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701301/
https://www.ncbi.nlm.nih.gov/pubmed/33304877
http://dx.doi.org/10.3389/fpubh.2020.584552
Descripción
Sumario:Interleukin 6 (IL-6) is one of the markers of immune system activation indicating existent infection and inflammation. We present here a case of a 55-year-old male COVID-19 patient with an unusual high level of interleukin 6 (IL-6). Further investigation revealed he had hepatocellular carcinoma (HCC) with underlying hepatitis B. He did not present with respiratory symptoms although a baseline chest x-ray showed changes, and the patient was categorized as Class 3A of COVID-19. Routine investigations proceeded with high-resolution computed tomography and IL-6 to monitor for progression to severe COVID-19. Notably, there was a high IL-6 level but other parameters did not show he was in severe COVID-19. In this report, we conclude that elevated IL-6 level in a COVID-19 patient is not necessarily associated with severe COVID-19.