Inhibition of IRE1/JNK pathway in HK‐2 cells subjected to hypoxia‐reoxygenation attenuates mesangial cells‐derived extracellular matrix production

Endoplasmic reticulum (ER) stress and inflammatory responses play active roles in the transition of acute kidney injury (AKI) to chronic kidney disease (CKD). Inositol‐requiring enzyme 1 (IRE1) activates c‐Jun NH(2)‐terminal kinase (JNK) in ER stress. Tubular epithelial cells (TEC) are the main inju...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Yan, Liang, Lulu, Liu, Zhenjie, Wang, Yingzi, Dong, Xiubing, Qu, Lingyun, Gou, Rong, Wang, Yulin, Wang, Qian, Liu, Zhangsuo, Tang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701502/
https://www.ncbi.nlm.nih.gov/pubmed/33043579
http://dx.doi.org/10.1111/jcmm.15964

Ejemplares similares

Ejemplares similares